Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | RECQL | P46063 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 6/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30279249 | 1.00 | ALDH1A1 (0.52) | ALDH1A1GAARECQLMAPTMEN1 | |
| SCHEMBL2811051 | 0.86 | TSHR (0.50) | ALDH1A1GAARECQLMAPTMEN1 | |
| SCHEMBL9612031 | 0.84 | TSHR (0.48) | ALDH1A1GAARECQLMAPTMEN1 | |
| SCHEMBL22280536 | 0.84 | CYP3A4 (0.48) | ALDH1A1GAARECQLMAPTMEN1 | |
| SCHEMBL14307623 | 0.83 | TSHR (0.46) | ALDH1A1GAARECQLMAPTMEN1 | |
| SCHEMBL3790287 | 0.82 | ALDH1A1 (0.57) | ALDH1A1GAARECQLMAPTMEN1 | |
| SCHEMBL4823779 | 0.79 | NPC1 (0.44) | ALDH1A1GAARECQLMAPTMEN1 | |
| SCHEMBL22280537 | 0.79 | ESR2 (0.50) | ALDH1A1GAARECQLMAPTMEN1 | |
| SCHEMBL11304152 | 0.79 | TSHR (0.52) | ALDH1A1GAARECQLMAPTMEN1 | |
| SCHEMBL256203 | 0.78 | ALDH1A1 (0.64) | ALDH1A1GAARECQLMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 141 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2007523865-A | — | — | 2007-08-23 | — | — | JP | claimed |
| US-7129235-B2 | Amides useful for treating pain | ABBOTT LABORATORIES (US) | 2006-10-31 | — | — | US | claimed |
| EP-1646621-A2 | NOVEL AZAHETEROCYCLIC AMIDES USEFUL FOR TREATING PAIN | Abbott Laboratories (US) | 2006-04-19 | — | — | EP | claimed |
| US-20050080095-A1 | administering a therapeuitcally effective amount of 3'-(trifluoromethyl)-N-{4-[(trifluoromethyl)sulfonyl]phenyl}-3,6-dihydro-2H-1,2'-bipyridine-4-carboxamide; antagonists of vanilloid receptor subtype I | ABBVIE INC. | 2005-04-14 | — | — | US | claimed |
| WO-2005007642-A2 | NOVEL AZAHETEROCYCLIC AMIDES USEFUL FOR TREATING PAIN | ABBOTT LABORATORIES (US) | 2005-01-27 | — | — | WO | claimed |
| CN-122010988-A | Organic compound and application thereof | 北京鼎材科技股份有限公司 | 2026-05-12 | — | — | CN | disclosed |
| WO-2025100475-A1 | COMPOSITION FOR IMAGE RECORDING AND METHOD FOR PRODUCING SAME | キヤノン株式会社 | 2025-05-15 | — | — | WO | disclosed |
| US-20240360114-A1 | FERROPTOSIS MODULATORS, PREPARATIONS, AND USES THEREOF | Sironax Ltd. (KY) | 2024-10-31 | — | — | US | disclosed |
| CN-118076581-A | Iron death modulators, their preparation and use | 维泰瑞隆有限公司 | 2024-05-24 | — | — | CN | disclosed |
| US-20230389423-A1 | HETEROCYCLIC COMPOUNDS FOR ORGANIC ELECTROLUMINESCENT DEVICES | UDC IRELAND LIMITED (IE) | 2023-11-30 | — | — | US | disclosed |
| US-20230389423-A1 | HETEROCYCLIC COMPOUNDS FOR ORGANIC ELECTROLUMINESCENT DEVICES | UDC IRELAND LIMITED (IE) | 2023-11-30 | — | — | US | disclosed |
| EP-4273151-A1 | NOVEL COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING SAME | Lg Chem, Ltd. (KR) | 2023-11-08 | — | — | EP | disclosed |
| US-5354869-A | Fluorescent dyes | RIEDEL-DE HAEN AKTIENGESELLSCHAFT (DE) | 1994-10-11 | — | — | US | disclosed |
| WO-1994015903-A1 | 3,3 DIPHENYL PROP-2-YL AMINO ACID DERIVATIVES AND THEIR USE AS TACHYKININ ANTAGONISTS | MERCK SHARP & DOHME LIMITED (GB) | 1994-07-21 | — | — | WO | disclosed |
| WO-1993021181-A1 | AZACYCLIC COMPOUNDS | MERCK SHARP & DOHME LIMITED (GB) | 1993-10-28 | — | — | WO | disclosed |
| EP-0426717-A1 | OPTICAL MEMORY. | RIEDEL DE HAEN AG (DE) | 1991-05-15 | — | — | EP | disclosed |
| WO-1990001480-A1 | OPTICAL MEMORY | RIEDEL-DE HAEN AKTIENGESELLSCHAFT (DE) | 1990-02-22 | — | — | WO | disclosed |
| EP-0069065-B1 | PROCESS FOR THE ALKYLATION OR ARALKYLATION OF AROMATIC AMINES | CIBA-GEIGY AG (CH) | 1985-02-13 | — | — | EP | disclosed |
| US-4436936-A | ACID CATALYSTS | CIBA-GEIGY CORPORATION (US) | 1984-03-13 | — | — | US | disclosed |
| EP-0069065-A1 | Process for the alkylation or aralkylation of aromatic amines | CIBA-GEIGY AG (CH) | 1983-01-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240360114-A1 | FERROPTOSIS MODULATORS, PREPARATIONS, AND USES THEREOF | AIFM2, GPX1, GPX4 | ALDH1A1 1441/4885GAA 771/4885RECQL 2962/4885 |
| US-20050080095-A1 | administering a therapeuitcally effective amount of 3'-(trifluoromethyl)-N-{4-[(trifluoromethyl)sulfonyl]phenyl}-3,6-dihydro-2H-1,2'-bipyridine-4-carboxamide; antagonists of vanilloid receptor subtype I | TRPV1, OPRL1, TRPV6 | ALDH1A1 843/4885GAA 2594/4885RECQL 1598/4885 |
| US-20230389423-A1 | HETEROCYCLIC COMPOUNDS FOR ORGANIC ELECTROLUMINESCENT DEVICES | DDT, VDAC2, KCNC1 | ALDH1A1 525/4885GAA 3115/4885RECQL 1281/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.