SCHEMBL25673152

SCHEMBL25673152

CNc1ccccc1/C=C/c1sc2ccc(-c3ccccc3)cc2c1C

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ROCK1 Q13464 1/20 0.39
TRIM58 Q8NG06 1/20 0.39
TUBB4A P04350 1/20 0.37
TUBB P07437 1/20 0.37
TUBA3C P0DPH7 1/20 0.37
TUBA1B P68363 1/20 0.37
TUBA4A P68366 1/20 0.37
TUBB4B P68371 1/20 0.37
TUBB3 Q13509 1/20 0.37
TUBB2A Q13885 1/20 0.37
TUBB8 Q3ZCM7 1/20 0.37
TUBA3E Q6PEY2 1/20 0.37
TUBA1A Q71U36 1/20 0.37
TUBA1C Q9BQE3 1/20 0.37
TUBB6 Q9BUF5 1/20 0.37
TUBB2B Q9BVA1 1/20 0.37
TUBB1 Q9H4B7 1/20 0.37
ACLY P53396 1/20 0.34
HTR6 P50406 1/20 0.33
LIMK1 P53667 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25520554 0.83 TUBB4A (0.48) ROCK1TUBB4ATUBBTUBA3CTUBA1B
SCHEMBL25681010 0.82 ROCK1 (0.46) ROCK1TRIM58TUBB4ATUBBTUBA3C
SCHEMBL24589255 0.74 ROCK1 (0.46) ROCK1TRIM58TUBB4ATUBBTUBA3C
SCHEMBL22140794 0.72 ROCK1 (0.44) ROCK1TRIM58TUBB4ATUBBTUBA3C
SCHEMBL13713795 0.69 ROCK1 (0.51) ROCK1TRIM58ACLYLIMK1PIM3
SCHEMBL19830171 0.68 ROCK1 (0.36) ROCK1TUBB4ATUBBTUBA3CTUBA1B
SCHEMBL25520949 0.67 LIMK1 (0.36) ACLYLIMK1
SCHEMBL6840354 0.66 GPR35 (0.55) ROCK1ACLYLIMK1PIM3
SCHEMBL14951612 0.66 TRIM58 (0.40) ROCK1TRIM58ACLYHTR6LIMK1
SCHEMBL29828944 0.65 LIMK1 (0.51) ROCK1TRIM58LIMK1PIM3PIM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230171979-A1 ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DEVICE HAVING THEREOF LG DISPLAY CO., LTD. (KR) 2023-06-01 US disclosed