Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.41 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.41 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.41 |
| ▸ | PPARD | Q03181 | 1/20 | 0.41 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.41 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9567295 | 0.92 | GPR84 (0.53) | GPR84FFAR1SLC1A2SLC1A1MAPT | |
| SCHEMBL28224631 | 0.86 | HDAC1 (0.48) | CA2MAPK1GPR84FFAR1SLC1A2 | |
| SCHEMBL31008464 | 0.84 | CA2 (0.50) | CA2MAPK1GPR84FFAR1SLC1A2 | |
| SCHEMBL169862 | 0.83 | CA2 (0.48) | CA2MAPK1GPR84FFAR1SLC1A2 | |
| SCHEMBL8525907 | 0.83 | CA2 (0.48) | CA2MAPK1GPR84FFAR1SLC1A2 | |
| SCHEMBL29023370 | 0.82 | TERT (0.50) | FFAR1MAPTPPARDCHRM1TDP1 | |
| SCHEMBL28234347 | 0.82 | TERT (0.50) | FFAR1MAPTPPARDCHRM1TDP1 | |
| SCHEMBL1119146 | 0.82 | TERT (0.50) | FFAR1MAPTPPARDCHRM1TDP1 | |
| SCHEMBL20448187 | 0.82 | TERT (0.50) | FFAR1MAPTPPARDCHRM1TDP1 | |
| SCHEMBL1119138 | 0.82 | TERT (0.50) | FFAR1MAPTPPARDCHRM1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103025738-A | Furopyridine compounds and uses thereof | NOVARTIS AG | 2013-04-03 | — | — | CN | disclosed |
| EP-2560976-A1 | FUROPYRIDINE COMPOUNDS AND USES THEREOF | Novartis AG (CH) | 2013-02-27 | — | — | EP | disclosed |
| WO-2011131709-A1 | FUROPYRIDINE COMPOUNDS AND USES THEREOF | NOVARTIS AG (CH) | 2011-10-27 | — | — | WO | disclosed |
| CN-1086996-A | Cosmetic composition | UNILEVER NV (NL) | 1994-05-25 | — | — | CN | disclosed |
| EP-0576287-A1 | Cosmetic compositions | UNILEVER PLC (GB) | 1993-12-29 | — | — | EP | disclosed |