Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | CCR5 | P51681 | 4/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26452750 | 1.00 | ALDH1A1 (0.40) | ALDH1A1MAPK1L3MBTL1CCR5CHRM2 | |
| SCHEMBL22891921 | 1.00 | ALDH1A1 (0.40) | ALDH1A1MAPK1L3MBTL1CCR5CHRM2 | |
| SCHEMBL25677093 | 1.00 | ALDH1A1 (0.40) | ALDH1A1MAPK1L3MBTL1CCR5CHRM2 | |
| SCHEMBL26452770 | 0.90 | ALDH1A1 (0.40) | ALDH1A1MAPK1L3MBTL1CCR5CHRM2 | |
| SCHEMBL19655812 | 0.88 | ALDH1A1 (0.43) | ALDH1A1MAPK1L3MBTL1CCR5CHRM2 | |
| SCHEMBL21484546 | 0.88 | ALDH1A1 (0.43) | ALDH1A1MAPK1L3MBTL1CCR5CHRM2 | |
| SCHEMBL19655862 | 0.88 | ALDH1A1 (0.43) | ALDH1A1MAPK1L3MBTL1CCR5CHRM2 | |
| SCHEMBL18845641 | 0.88 | ALDH1A1 (0.43) | ALDH1A1MAPK1L3MBTL1CCR5CHRM2 | |
| SCHEMBL26452726 | 0.87 | ALDH1A1 (0.43) | ALDH1A1MAPK1L3MBTL1CCR5CHRM2 | |
| SCHEMBL26452696 | 0.85 | CPB1 (0.45) | ALDH1A1MAPK1L3MBTL1CHRM2CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11680069-B2 | Processes for the preparation of (3S,4R)-3-ethyl-4-(3H-imidazo[1,2-a]pyrrolo[2,3-e]-pyrazin-8-yl)-n-(2,2,2-trifluoroethyl)pyrrolidine-1-carboxamide and solid state forms thereof | ABBVIE INC. (US) | 2023-06-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11680069-B2 | Processes for the preparation of (3S,4R)-3-ethyl-4-(3H-imidazo[1,2-a]pyrrolo[2,3-e]-pyrazin-8-yl)-n-(2,2,2-trifluoroethyl)pyrrolidine-1-carboxamide and solid state forms thereof | CNKSR1, JAK2, TNF | ALDH1A1 600/4885MAPK1 3184/4885L3MBTL1 4848/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.