Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPB1 | P15086 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18845641 | 0.89 | ALDH1A1 (0.43) | CYP2C9CYP2C19ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL19655812 | 0.89 | ALDH1A1 (0.43) | CYP2C9CYP2C19ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL21484546 | 0.89 | ALDH1A1 (0.43) | CYP2C9CYP2C19ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL19655862 | 0.89 | ALDH1A1 (0.43) | CYP2C9CYP2C19ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL26452726 | 0.88 | ALDH1A1 (0.43) | CYP2C9CYP2C19ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL26452770 | 0.86 | ALDH1A1 (0.40) | CYP2C9CYP2C19ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL26452668 | 0.85 | ALDH1A1 (0.38) | CYP2C9CYP2C19ALDH1A1CYP1A2CHRM2 | |
| SCHEMBL26452466 | 0.85 | CHRM5 (0.36) | CPB1CYP2C9CYP2C19ALDH1A1CYP1A2 | |
| SCHEMBL26452546 | 0.85 | CHRM5 (0.36) | CPB1CYP2C9CYP2C19ALDH1A1CYP1A2 | |
| SCHEMBL26452643 | 0.85 | CHRM5 (0.36) | CPB1CYP2C9CYP2C19ALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230139156-A1 | PROCESS AND INTERMEDIATES FOR THE PREPARATION OF UPADACITINIB | CURIA SPAIN, S.A.U. (ES) | 2023-05-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230139156-A1 | PROCESS AND INTERMEDIATES FOR THE PREPARATION OF UPADACITINIB | CDK19, CDK11B, CDK9 | CPB1 1890/4885CYP2C9 82/4885CYP2C19 63/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.