SCHEMBL25675892

SCHEMBL25675892

Clc1ccc(-c2nc(-c3cccc4ccccc34)cs2)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 7/20 0.55
SMN1; SMN2 Q16637 7/20 0.55
KDM4E B2RXH2 5/20 0.55
LMNA P02545 1/20 0.55
NPC1 O15118 4/20 0.54
CYP19A1 P11511 3/20 0.52
CRHBP P24387 1/20 0.52
CRHR2 Q13324 1/20 0.52
CASP3 P42574 1/20 0.50
SENP8 Q96LD8 1/20 0.50
SENP7 Q9BQF6 1/20 0.50
SENP6 Q9GZR1 1/20 0.50
THRB P10828 1/20 0.49
MEN1 O00255 2/20 0.49
KMT2A Q03164 2/20 0.49
ALDH1A1 P00352 2/20 0.48
MAPT P10636 2/20 0.48
MAPK1 P28482 1/20 0.48
GPR55 Q9Y2T6 1/20 0.47
AR P10275 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11466274 0.91 CYP19A1 (0.59) RAB9ASMN1; SMN2KDM4ELMNANPC1
SCHEMBL23212840 0.85 RAB9A (0.62) RAB9ASMN1; SMN2KDM4ELMNANPC1
SCHEMBL14378910 0.80 KDM4E (0.75) RAB9ASMN1; SMN2KDM4ELMNANPC1
SCHEMBL5254898 0.80 KMT2A (0.54) RAB9ASMN1; SMN2KDM4ENPC1CYP19A1
SCHEMBL4281217 0.78 RAB9A (0.75) RAB9ASMN1; SMN2KDM4ELMNANPC1
SCHEMBL11454418 0.78 KMT2A (0.59) RAB9ASMN1; SMN2KDM4ENPC1CYP19A1
SCHEMBL11455457 0.78 RAB9A (0.75) RAB9ASMN1; SMN2KDM4ELMNANPC1
SCHEMBL14531227 0.78 SMN1; SMN2 (0.71) RAB9ASMN1; SMN2KDM4ELMNANPC1
SCHEMBL11466217 0.77 KDM4E (0.86) RAB9ASMN1; SMN2KDM4ELMNANPC1
SCHEMBL29654261 0.76 MPL (0.53) RAB9ASMN1; SMN2KDM4ELMNANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023106625-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME 엘티소재주식회사 2023-06-15 WO disclosed