Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPL | P40238 | 3/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 6/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.50 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.44 |
| ▸ | RELA | Q04206 | 2/20 | 0.44 |
| ▸ | AR | P10275 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL713110 | 0.92 | HSD17B10 (0.61) | MPLHSD17B10RAB9AALDH1A1MEN1 | |
| Bromide SCHEMBL8357463 | 0.90 | HSD17B10 (0.59) | MPLHSD17B10RAB9AALDH1A1MEN1 | |
| SCHEMBL29654229 | 0.83 | CYP19A1 (0.63) | MPLHSD17B10RAB9AALDH1A1MEN1 | |
| SCHEMBL29654188 | 0.81 | MPL (0.43) | MPLHSD17B10RAB9AALDH1A1MEN1 | |
| SCHEMBL29654224 | 0.79 | MPL (0.84) | MPLHSD17B10RAB9AALDH1A1MEN1 | |
| SCHEMBL5254898 | 0.79 | KMT2A (0.54) | RAB9AALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL9830320 | 0.78 | HTR2C (0.45) | MPLHSD17B10ALDH1A1MEN1KMT2A | |
| SCHEMBL23212840 | 0.78 | RAB9A (0.62) | HSD17B10RAB9AALDH1A1MEN1KMT2A | |
| SCHEMBL12592171 | 0.78 | MPL (0.56) | MPLHSD17B10RAB9AALDH1A1MEN1 | |
| SCHEMBL11454418 | 0.77 | KMT2A (0.59) | HSD17B10RAB9AALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114249702-A | N-aryl- [2,4 '-bithiazole ] -2' -amine compound and preparation and application thereof | 沈阳药科大学 | 2022-03-29 | — | — | CN | disclosed |