SCHEMBL2567893

SCHEMBL2567893

CC(C)(C)OC(=O)C(O)CCCCCN

nearest known ligand 0.46

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CPB2 Q96IY4 6/20 0.46
GSR P00390 1/20 0.37
GPR84 Q9NQS5 3/20 0.36
RNPEP Q9H4A4 1/20 0.36
FFAR1 O14842 1/20 0.36
PAOX Q6QHF9 1/20 0.35
GNAI3 P08754 1/20 0.34
GNAO1 P09471 1/20 0.34
GNAI1 P63096 1/20 0.34
NOS1 P29475 2/20 0.33
MEN1 O00255 1/20 0.33
GAA P10253 1/20 0.33
KMT2A Q03164 1/20 0.33
ACACB O00763 1/20 0.33
ACACA Q13085 1/20 0.33
NOS3 P29474 1/20 0.33
NOS2 P35228 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL133019 0.98 CPB2 (0.44) CPB2GSRGPR84RNPEPFFAR1
SCHEMBL2177004 0.93 CPB2 (0.38) CPB2GSRGPR84RNPEPFFAR1
SCHEMBL9242626 0.91 GPR84 (0.42) CPB2GPR84FFAR1NOS1MEN1
SCHEMBL6537553 0.90 CPB2 (0.39) CPB2GSRRNPEPNOS1MEN1
SCHEMBL6797401 0.85 NOS1 (0.36) CPB2NOS1MEN1GAAKMT2A
SCHEMBL7110422 0.85 NOS1 (0.36) CPB2NOS1MEN1GAAKMT2A
SCHEMBL28189283 0.85 CPB2 (0.40) CPB2GSRGPR84RNPEPPAOX
SCHEMBL27493572 0.84 TDP1 (0.47) GPR84FFAR1NOS1MEN1GAA
SCHEMBL28636377 0.84 GPR84 (0.55) GPR84FFAR1
SCHEMBL5593600 0.84 GPR84 (0.55) GPR84FFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118619952-A Aloperine derivative, preparation method, pharmaceutical composition and application thereof 中国医学科学院药物研究所 2024-09-10 CN disclosed
CN-104936591-B Hematopoietin expression facilitator 国立大学法人东北大学 2018-05-29 CN disclosed
WO-2011131731-A1 CYCLOPEPTIDE DERIVATIVES AND USES THEREOF Technische Universität München (DE) 2011-10-27 WO disclosed
EP-1171442-A1 XANTHINE DERIVATIVES AND ANALOGS AS CELL SIGNALLING INHIBITORS CELL THERAPEUTICS, INC. (US) 2002-01-16 EP disclosed
WO-2000061583-A1 XANTHINE DERIVATIVES AND ANALOGS AS CELL SIGNALING INHIBITORS CELL THERAPEUTICS, INC. (US) 2000-10-19 WO disclosed