Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FURIN | P09958 | 2/20 | 0.40 |
| ▸ | SIRT2 | Q8IXJ6 | 8/20 | 0.40 |
| ▸ | SIRT1 | Q96EB6 | 7/20 | 0.40 |
| ▸ | SIRT3 | Q9NTG7 | 3/20 | 0.40 |
| ▸ | CHRNA1 | P02708 | 2/20 | 0.39 |
| ▸ | CHRNG | P07510 | 2/20 | 0.39 |
| ▸ | CHRNB1 | P11230 | 2/20 | 0.39 |
| ▸ | CHRND | Q07001 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | FAP | Q12884 | 2/20 | 0.38 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.37 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.37 |
| ▸ | CTSD | P07339 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18459644 | 0.92 | SIRT2 (0.42) | FURINSIRT2SIRT1SIRT3CHRNA1 | |
| SCHEMBL24774284 | 0.92 | FURIN (0.40) | FURINSIRT2SIRT1SIRT3CHRNA1 | |
| SCHEMBL17490743 | 0.91 | SIRT2 (0.41) | FURINSIRT2SIRT1SIRT3CHRNA1 | |
| SCHEMBL27278330 | 0.91 | SIRT2 (0.41) | FURINSIRT2SIRT1SIRT3CHRNA1 | |
| SCHEMBL25726157 | 0.90 | CHRND (0.41) | FURINCHRNA1CHRNGCHRNB1CHRND | |
| SCHEMBL25726153 | 0.90 | CHRND (0.41) | FURINCHRNA1CHRNGCHRNB1CHRND | |
| SCHEMBL23515087 | 0.90 | SIRT2 (0.46) | FURINSIRT2SIRT1SIRT3 | |
| SCHEMBL24164331 | 0.88 | FAP (0.41) | FURINSIRT2SIRT1SIRT3HTT | |
| SCHEMBL25680714 | 0.88 | FAP (0.43) | FURINSIRT2SIRT1SIRT3HTT | |
| SCHEMBL19681567 | 0.88 | FURIN (0.39) | FURINCHRNA1CHRNGCHRNB1CHRND |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023109942-A1 | COMPOUND-LINKER CONSTRUCTS COMPRISING NOVEL COMPOUNDS USEFUL AS STING AGONISTS AND USES THEREOF | JACOBIO PHARMACEUTICALS CO., LTD. (CN) | 2023-06-22 | — | — | WO | disclosed |