Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FURIN | P09958 | 3/20 | 0.40 |
| ▸ | MAP1LC3B | Q9GZQ8 | 2/20 | 0.36 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SIRT2 | Q8IXJ6 | 6/20 | 0.35 |
| ▸ | SIRT1 | Q96EB6 | 5/20 | 0.35 |
| ▸ | SIRT3 | Q9NTG7 | 3/20 | 0.35 |
| ▸ | NPY1R | P25929 | 1/20 | 0.35 |
| ▸ | NPY2R | P49146 | 1/20 | 0.35 |
| ▸ | NPY4R | P50391 | 1/20 | 0.35 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.35 |
| ▸ | CHRNG | P07510 | 1/20 | 0.35 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.35 |
| ▸ | CHRND | Q07001 | 1/20 | 0.35 |
| ▸ | FAP | Q12884 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22138374 | 0.92 | SIRT5 (0.38) | FURINMAP1LC3BSIRT5HTTSIRT2 | |
| SCHEMBL22138373 | 0.92 | FURIN (0.45) | FURINMAP1LC3BHTTSIRT2SIRT1 | |
| SCHEMBL25680283 | 0.92 | FURIN (0.40) | FURINMAP1LC3BSIRT5HTTSIRT2 | |
| SCHEMBL22702534 | 0.91 | TRPV1 (0.39) | FURINMAP1LC3BHTTNPY1RNPY2R | |
| SCHEMBL27434308 | 0.90 | FURIN (0.39) | FURINMAP1LC3BSIRT5HTTNPY1R | |
| SCHEMBL24164331 | 0.88 | FAP (0.41) | FURINMAP1LC3BSIRT5HTTSIRT2 | |
| SCHEMBL19681567 | 0.88 | FURIN (0.39) | FURINMAP1LC3BSIRT5HTTNPY1R | |
| SCHEMBL25839420 | 0.86 | SIRT2 (0.38) | FURINMAP1LC3BSIRT5HTTSIRT2 | |
| SCHEMBL23051312 | 0.86 | MAP1LC3B (0.38) | FURINMAP1LC3BSIRT5HTTSIRT2 | |
| SCHEMBL25730962 | 0.86 | SIRT2 (0.36) | FURINMAP1LC3BSIRT5SIRT2SIRT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022253033-A1 | CHEMICAL COUPLING LINKER AND USE THEREOF | 四川科伦博泰生物医药股份有限公司 | 2022-12-08 | — | — | WO | disclosed |