Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.36 |
| ▸ | NQO2 | P16083 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | GPR3 | P46089 | 1/20 | 0.36 |
| ▸ | RORA | P35398 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | RORB | Q92753 | 1/20 | 0.36 |
| ▸ | RXRA | P19793 | 1/20 | 0.35 |
| ▸ | RXRB | P28702 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25683515 | 0.91 | KDM4E (0.38) | HPGDKDM4EALDH1A1HSD17B10MAPT | |
| SCHEMBL25683449 | 0.91 | HPGD (0.39) | HPGDKDM4EALDH1A1HSD17B10UTS2R | |
| SCHEMBL25683516 | 0.90 | HPGD (0.40) | HPGDKDM4EALDH1A1HSD17B10UTS2R | |
| SCHEMBL25682438 | 0.86 | RORA (0.41) | HPGDKDM4EALDH1A1HSD17B10UTS2R | |
| SCHEMBL25684442 | 0.85 | UTS2R (0.38) | HPGDKDM4EALDH1A1HSD17B10UTS2R | |
| SCHEMBL25684079 | 0.84 | ALKBH5 (0.39) | HPGDKDM4EALDH1A1HSD17B10MAPT | |
| SCHEMBL25684445 | 0.81 | HPGD (0.39) | HPGDKDM4EALDH1A1HSD17B10UTS2R | |
| SCHEMBL13183789 | 0.81 | GPR3 (0.47) | HPGDKDM4EALDH1A1HSD17B10UTS2R | |
| SCHEMBL25684320 | 0.81 | HPGD (0.40) | HPGDKDM4EALDH1A1HSD17B10UTS2R | |
| SCHEMBL19652611 | 0.81 | KDM4E (0.40) | HPGDKDM4EALDH1A1HSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4190791-A1 | COMPOUND, LIGHT-EMITTING MATERIAL, AND LIGHT-EMITTING ELEMENT | Kyulux, Inc. (JP) | 2023-06-07 | — | — | EP | disclosed |
| US-20170158683-A1 | COMPOSITIONS AND METHODS FOR INHIBITION OF THE JAK PATHWAY | RIGEL PHARMACEUTICALS, INC. (US) | 2017-06-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170158683-A1 | COMPOSITIONS AND METHODS FOR INHIBITION OF THE JAK PATHWAY | JAK3, JAK2, JAK1 | HPGD 1411/4885KDM4E 2724/4885ALDH1A1 3686/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.