Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | IDH1 | O75874 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | GBA1 | P04062 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2569125 | 0.89 | MAPT (0.39) | MAPTSMN1; SMN2RAB9ANPC1SLC6A3 | |
| SCHEMBL1595904 | 0.86 | MAPT (0.42) | MAPTSMN1; SMN2RAB9ANPC1SLC6A3 | |
| SCHEMBL2572026 | 0.85 | P2RX7 (0.48) | MAPTSMN1; SMN2KMT2APOLBTP53 | |
| SCHEMBL2565938 | 0.85 | ALOX5 (0.40) | MAPTSMN1; SMN2RAB9ANPC1POLB | |
| SCHEMBL2572466 | 0.84 | MAPK1 (0.37) | MAPTSMN1; SMN2RAB9ANPC1SLC6A3 | |
| SCHEMBL2570520 | 0.84 | MEN1 (0.39) | MAPTSMN1; SMN2RAB9ANPC1SLC6A3 | |
| SCHEMBL2570875 | 0.84 | MAPK1 (0.37) | MAPTSMN1; SMN2RAB9ANPC1SLC6A3 | |
| SCHEMBL2567127 | 0.81 | GRIK1 (0.42) | MAPTRAB9AMEN1KMT2ATP53 | |
| SCHEMBL13197811 | 0.78 | EPHX2 (0.38) | MAPTSMN1; SMN2RAB9ANPC1SLC6A3 | |
| SCHEMBL2569122 | 0.77 | MAPT (0.40) | MAPTSMN1; SMN2RAB9ANPC1SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1732901-B1 | ANTIVIRAL 4-AMINOCARBONYLAMINO-SUBSTITUTED IMIDAZOLE COMPOUND | AICURIS GMBH & CO KG (DE) | 2011-11-02 | — | — | EP | disclosed |
| EP-1853582-B1 | HETEROCYCLYLAMIDE-SUBSTITUTED IMIDAZOLES | AICURIS GMBH & CO KG (DE) | 2009-10-21 | — | — | EP | disclosed |
| EP-1732901-A1 | ANTIVIRAL 4-AMINOCARBONYLAMINO-SUBSTITUTED IMIDAZOLE COMPOUND | Bayer HealthCare AG (DE) | 2006-12-20 | — | — | EP | disclosed |
| WO-2005092865-A1 | ANTIVIRAL 4-AMINOCARBONYLAMINO-SUBSTITUTED IMIDAZOLE COMPOUND | BAYER HEALTHCARE AG (DE) | 2005-10-06 | — | — | WO | disclosed |