Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 7/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | RAF1 | P04049 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2567127 | 0.89 | GRIK1 (0.42) | P2RX7LMNAKMT2AGAARAF1 | |
| SCHEMBL2565938 | 0.86 | ALOX5 (0.40) | P2RX7POLBSMN1; SMN2GAAL3MBTL1 | |
| SCHEMBL2569125 | 0.85 | MAPT (0.39) | P2RX7POLBKMT2ASMN1; SMN2GAA | |
| SCHEMBL2568640 | 0.85 | MAPT (0.39) | POLBLMNAKMT2ASMN1; SMN2GAA | |
| SCHEMBL2572024 | 0.85 | P2RX7 (0.48) | P2RX7POLBLMNAKMT2ASMN1; SMN2 | |
| SCHEMBL2572466 | 0.85 | MAPK1 (0.37) | P2RX7POLBKMT2ASMN1; SMN2RAF1 | |
| SCHEMBL2570875 | 0.85 | MAPK1 (0.37) | P2RX7POLBKMT2ASMN1; SMN2KDR | |
| SCHEMBL2570520 | 0.85 | MEN1 (0.39) | POLBLMNAKMT2ASMN1; SMN2GAA | |
| SCHEMBL13197798 | 0.78 | P2RX7 (0.45) | P2RX7POLBLMNAKMT2ASMN1; SMN2 | |
| SCHEMBL13197922 | 0.77 | LMNA (0.48) | LMNASMN1; SMN2GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1732901-B1 | ANTIVIRAL 4-AMINOCARBONYLAMINO-SUBSTITUTED IMIDAZOLE COMPOUND | AICURIS GMBH & CO KG (DE) | 2011-11-02 | — | — | EP | disclosed |