Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.44 |
| ▸ | MEN1 | O00255 | 5/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.43 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25688632 | 0.78 | RECQL (0.39) | ALDH1A1SMN1; SMN2KDM4ERECQLTSHR | |
| SCHEMBL25687805 | 0.70 | RECQL (0.44) | MAPK1ALDH1A1SMN1; SMN2KDM4EGAA | |
| SCHEMBL16367135 | 0.69 | KMT2A (0.41) | KMT2AMEN1HTTAPOBEC3AAPOBEC3G | |
| SCHEMBL295502 | 0.68 | SLC6A2 (0.49) | KMT2AMEN1SMN1; SMN2SLC6A2SLC6A4 | |
| SCHEMBL1088404 | 0.68 | SLC6A2 (0.44) | KMT2AMEN1MAPK1SMN1; SMN2SLC6A2 | |
| SCHEMBL8484000 | 0.67 | ALDH1A1 (0.35) | KMT2AMEN1HTTALDH1A1SMN1; SMN2 | |
| SCHEMBL18494973 | 0.67 | EPHX1 (0.34) | HTTALDH1A1SMN1; SMN2KDM4EGAA | |
| SCHEMBL13770854 | 0.67 | SLC6A2 (0.48) | KMT2AMEN1ALDH1A1SMN1; SMN2SLC6A2 | |
| Hydrochloric Acid SCHEMBL8483997 | 0.66 | L3MBTL1 (0.36) | KMT2AMEN1HTTALDH1A1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL8838006 | 0.66 | GNAI3 (0.54) | HTTALDH1A1SMN1; SMN2KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023114379-A1 | PLPRO INHIBITORS | HUAHAI US INC. (US) | 2023-06-22 | — | — | WO | disclosed |