Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 2/20 | 0.43 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.43 |
| ▸ | MELK | Q14680 | 6/20 | 0.41 |
| ▸ | F10 | P00742 | 3/20 | 0.41 |
| ▸ | FLT3 | P36888 | 2/20 | 0.38 |
| ▸ | CAMK2G | Q13555 | 1/20 | 0.38 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.38 |
| ▸ | MYLK | Q15746 | 1/20 | 0.38 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2566741 | 0.85 | F10 (0.44) | ARF10 | |
| SCHEMBL2563178 | 0.85 | F10 (0.41) | ARF10 | |
| SCHEMBL2569663 | 0.85 | F10 (0.41) | ARF10 | |
| SCHEMBL2567220 | 0.84 | F10 (0.44) | ARF10 | |
| SCHEMBL3034870 | 0.84 | AR (0.62) | ARSLC2A1MELKF10 | |
| SCHEMBL2567658 | 0.83 | F10 (0.44) | ARF10 | |
| SCHEMBL2569694 | 0.82 | F10 (0.42) | ARF10 | |
| SCHEMBL2570187 | 0.82 | F10 (0.33) | ARF10 | |
| SCHEMBL2574252 | 0.78 | F10 (0.42) | ARF10 | |
| SCHEMBL2568969 | 0.77 | RAB9A (0.36) | ARF10HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1899330-B9 | SUBSTITUTED GLYCINAMIDES HAVING AN ANTITHROMBOTIC AND FACTOR XA-INHIBITING EFFECT | BOEHRINGER INGELHEIM INT (DE) | 2011-11-09 | — | — | EP | disclosed |
| EP-1899330-B1 | SUBSTITUTED GLYCINAMIDES HAVING AN ANTITHROMBOTIC AND FACTOR XA-INHIBITING EFFECT | BOEHRINGER INGELHEIM INT (DE) | 2010-11-24 | — | — | EP | disclosed |