Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 3/20 | 0.44 |
| ▸ | AR | P10275 | 2/20 | 0.43 |
| ▸ | ESR1 | P03372 | 4/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | KCNA1 | Q09470 | 3/20 | 0.35 |
| ▸ | KCNAB1 | Q14722 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | AXL | P30530 | 1/20 | 0.34 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.34 |
| ▸ | MERTK | Q12866 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2566741 | 0.90 | F10 (0.44) | F10ARKCNA1KCNAB1NPC1 | |
| SCHEMBL3025755 | 0.86 | AR (0.60) | F10ARESR1ESR2TRPV1 | |
| SCHEMBL2569663 | 0.85 | F10 (0.41) | F10ARNPC1RAB9AKDM4E | |
| SCHEMBL2563178 | 0.85 | F10 (0.41) | F10ARKCNA1KCNAB1NPC1 | |
| SCHEMBL2567220 | 0.85 | F10 (0.44) | F10ARNPC1RAB9AAXL | |
| SCHEMBL2569694 | 0.83 | F10 (0.42) | F10ARNPC1RAB9A | |
| SCHEMBL2569045 | 0.83 | AR (0.43) | F10AR | |
| SCHEMBL2571139 | 0.78 | DRD2 (0.42) | F10ARKCNA1KCNAB1NPC1 | |
| SCHEMBL2568969 | 0.78 | RAB9A (0.36) | F10ARNPC1RAB9A | |
| SCHEMBL2574252 | 0.77 | F10 (0.42) | F10AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1899330-B9 | SUBSTITUTED GLYCINAMIDES HAVING AN ANTITHROMBOTIC AND FACTOR XA-INHIBITING EFFECT | BOEHRINGER INGELHEIM INT (DE) | 2011-11-09 | — | — | EP | disclosed |
| EP-1899330-B1 | SUBSTITUTED GLYCINAMIDES HAVING AN ANTITHROMBOTIC AND FACTOR XA-INHIBITING EFFECT | BOEHRINGER INGELHEIM INT (DE) | 2010-11-24 | — | — | EP | disclosed |