Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 9/20 | 0.38 |
| ▸ | PRKAB2 | O43741 | 2/20 | 0.35 |
| ▸ | PRKAG1 | P54619 | 2/20 | 0.35 |
| ▸ | PRKAA2 | P54646 | 2/20 | 0.35 |
| ▸ | PRKAA1 | Q13131 | 2/20 | 0.35 |
| ▸ | PRKAG3 | Q9UGI9 | 2/20 | 0.35 |
| ▸ | PRKAG2 | Q9UGJ0 | 2/20 | 0.35 |
| ▸ | PRKAB1 | Q9Y478 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1128278 | 0.92 | CNR1 (0.39) | CNR1PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL1128119 | 0.86 | CNR1 (0.42) | CNR1 | |
| SCHEMBL1986400 | 0.81 | CNR1 (0.53) | CNR1 | |
| SCHEMBL1127923 | 0.79 | F10 (0.40) | CNR1PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL2568495 | 0.76 | CNR1 (0.54) | CNR1 | |
| SCHEMBL1989137 | 0.75 | CNR1 (0.53) | CNR1 | |
| SCHEMBL2567965 | 0.75 | CNR1 (0.53) | CNR1 | |
| SCHEMBL1127743 | 0.75 | CNR1 (0.53) | CNR1 | |
| SCHEMBL1128279 | 0.75 | CNR1 (0.55) | CNR1 | |
| SCHEMBL1989851 | 0.74 | CNR1 (0.53) | CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2283008-B1 | PYRROLE DERIVATIVES, PREPARATION OF SAME AND THERAPEUTIC APPLICATION THEREOF | SANOFI SA (FR) | 2011-11-02 | — | — | EP | disclosed |