Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 3/20 | 0.40 |
| ▸ | CNR1 | P21554 | 5/20 | 0.34 |
| ▸ | PRKAB2 | O43741 | 2/20 | 0.34 |
| ▸ | PRKAG1 | P54619 | 2/20 | 0.34 |
| ▸ | PRKAA2 | P54646 | 2/20 | 0.34 |
| ▸ | PRKAA1 | Q13131 | 2/20 | 0.34 |
| ▸ | PRKAG3 | Q9UGI9 | 2/20 | 0.34 |
| ▸ | PRKAG2 | Q9UGJ0 | 2/20 | 0.34 |
| ▸ | PRKAB1 | Q9Y478 | 2/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2569129 | 0.79 | CNR1 (0.38) | CNR1PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL1128278 | 0.71 | CNR1 (0.39) | CNR1PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL1985672 | 0.68 | PRKAB2 (0.47) | CNR1PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL1986400 | 0.68 | CNR1 (0.53) | CNR1 | |
| SCHEMBL14713225 | 0.65 | CNR1 (0.43) | CNR1PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL1260985 | 0.64 | CNR1 (0.59) | CNR1 | |
| SCHEMBL1128119 | 0.63 | CNR1 (0.42) | CNR1 | |
| SCHEMBL1260019 | 0.62 | CNR1 (0.68) | CNR1HTR2A | |
| SCHEMBL2568495 | 0.62 | CNR1 (0.54) | CNR1 | |
| SCHEMBL1127889 | 0.62 | CNR1 (0.40) | CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2283008-A2 | PYRROLE DERIVATIVES, PREPARATION OF SAME AND THERAPEUTIC APPLICATION THEREOF | Sanofi-aventis (FR) | 2011-02-16 | — | — | EP | disclosed |
| WO-2009141533-A2 | PYRROLE DERIVATIVES, PREPARATION OF SAME AND THERAPEUTIC APPLICATION THEREOF | SANOFI-AVENTIS (FR) | 2009-11-26 | — | — | WO | disclosed |