Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 10/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD1 | P21728 | 1/20 | 0.34 |
| ▸ | DRD5 | P21918 | 1/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.33 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.33 |
| ▸ | CCKBR | P32239 | 1/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3378613 | 0.92 | DRD2 (0.35) | F10DRD2DRD1DRD5ABCB1 | |
| SCHEMBL2572272 | 0.91 | F10 (0.36) | F10DRD2CCKBRROCK2 | |
| SCHEMBL2574027 | 0.91 | F10 (0.36) | F10DRD2CCKBRROCK2 | |
| SCHEMBL3382957 | 0.89 | F10 (0.44) | F10DRD2CCKBRMCHR1ROCK2 | |
| SCHEMBL2567354 | 0.89 | HTT (0.38) | F10NPC1RAB9ACCKBRROCK2 | |
| SCHEMBL2571974 | 0.88 | F10 (0.38) | F10CCKBRROCK2 | |
| SCHEMBL2572188 | 0.88 | F10 (0.37) | F10CCKBRROCK2 | |
| SCHEMBL2563134 | 0.88 | CA1 (0.39) | F10DRD2NPC1RAB9ACCKBR | |
| SCHEMBL2565521 | 0.88 | F10 (0.36) | F10CCKBRROCK2 | |
| SCHEMBL2571141 | 0.87 | CCKBR (0.38) | NPC1RAB9ACCKBRROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1899330-B9 | SUBSTITUTED GLYCINAMIDES HAVING AN ANTITHROMBOTIC AND FACTOR XA-INHIBITING EFFECT | BOEHRINGER INGELHEIM INT (DE) | 2011-11-09 | — | — | EP | disclosed |
| EP-1899330-B1 | SUBSTITUTED GLYCINAMIDES HAVING AN ANTITHROMBOTIC AND FACTOR XA-INHIBITING EFFECT | BOEHRINGER INGELHEIM INT (DE) | 2010-11-24 | — | — | EP | disclosed |