Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.35 |
| ▸ | DRD1 | P21728 | 1/20 | 0.35 |
| ▸ | DRD5 | P21918 | 1/20 | 0.35 |
| ▸ | F10 | P00742 | 11/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.33 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2569575 | 0.92 | F10 (0.36) | DRD2DRD1DRD5F10ABCB1 | |
| SCHEMBL2572758 | 0.91 | F10 (0.35) | DRD2F10ROCK2HTR2CDRD3 | |
| SCHEMBL2569505 | 0.90 | NPC1 (0.37) | DRD2DRD1DRD5ABCB1MCHR1 | |
| SCHEMBL3380237 | 0.88 | CCKBR (0.35) | DRD2F10ROCK2HTR2CDRD3 | |
| SCHEMBL2580055 | 0.88 | CA1 (0.40) | DRD2F10ROCK2NPC1RAB9A | |
| SCHEMBL2568508 | 0.88 | F10 (0.35) | DRD2F10ROCK2HTR2CDRD3 | |
| SCHEMBL3382957 | 0.87 | F10 (0.44) | DRD2F10MCHR1ROCK2HTR2C | |
| SCHEMBL2569708 | 0.87 | ROCK2 (0.39) | ROCK2NPC1RAB9A | |
| SCHEMBL2565436 | 0.87 | CCKBR (0.38) | F10ROCK2POLB | |
| SCHEMBL3032186 | 0.86 | F10 (0.47) | F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1899330-B1 | SUBSTITUTED GLYCINAMIDES HAVING AN ANTITHROMBOTIC AND FACTOR XA-INHIBITING EFFECT | BOEHRINGER INGELHEIM INT (DE) | 2010-11-24 | — | — | EP | disclosed |