SCHEMBL25695863

SCHEMBL25695863

OB(O)c1ccc2c(c1)sc1ccc3sc4ccccc4c3c12

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 6/20 0.44
▸ ALDH1A1 P00352 4/20 0.44
▸ RAB9A P51151 3/20 0.44
▸ HPGD P15428 2/20 0.44
▸ SMN1; SMN2 Q16637 1/20 0.44
▸ GPR3 P46089 1/20 0.43
▸ MAOA P21397 1/20 0.41
▸ MAOB P27338 1/20 0.41
▸ CA1 P00915 2/20 0.40
▸ CA2 P00918 2/20 0.40
▸ KDM4E B2RXH2 2/20 0.40
▸ MEN1 O00255 2/20 0.39
▸ POLB P06746 2/20 0.39
▸ KMT2A Q03164 2/20 0.39
▸ TDP1 Q9NUW8 2/20 0.39
▸ DUSP3 P51452 2/20 0.39
▸ BLM P54132 1/20 0.39
▸ PTPN5 P54829 1/20 0.39
▸ PTPN11 Q06124 1/20 0.39
▸ MCL1 Q07820 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25695834 0.91 GPR3 (0.45) MAPTALDH1A1RAB9AHPGDSMN1; SMN2
SCHEMBL2158388 0.91 GPR3 (0.54) MAPTALDH1A1RAB9AHPGDSMN1; SMN2
SCHEMBL29418151 0.91 GPR3 (0.54) MAPTALDH1A1RAB9AHPGDSMN1; SMN2
SCHEMBL18121134 0.87 CA1 (0.47) MAPTALDH1A1RAB9AHPGDSMN1; SMN2
SCHEMBL24398652 0.85 KDM4E (0.54) MAPTALDH1A1RAB9AHPGDSMN1; SMN2
SCHEMBL25490982 0.84 MAPT (0.44) MAPTALDH1A1RAB9AHPGDSMN1; SMN2
SCHEMBL31818 0.84 GPR3 (0.54) MAPTALDH1A1RAB9AHPGDSMN1; SMN2
SCHEMBL25171452 0.84 MGAM (0.35) MAPTALDH1A1RAB9AHPGDSMN1; SMN2
SCHEMBL22700242 0.82 MAPK1 (0.40) MAPTALDH1A1CA1CA2KDM4E
SCHEMBL25643863 0.82 MGLL (0.44) MAPTALDH1A1RAB9AHPGDSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230141820-A1 LIGHT EMITTING ELEMENT AND POLYCYCLIC COMPOUND FOR THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2023-05-11 — — US disclosed
US-20230141820-A1 LIGHT EMITTING ELEMENT AND POLYCYCLIC COMPOUND FOR THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2023-05-11 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230141820-A1 LIGHT EMITTING ELEMENT AND POLYCYCLIC COMPOUND FOR THE SAME TPH1, HTR1D, ECE1 MAPT 2754/4885ALDH1A1 392/4885RAB9A 3814/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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