Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.52 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.52 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
| ▸ | DAGLB | Q8NCG7 | 3/20 | 0.48 |
| ▸ | DPP4 | P27487 | 1/20 | 0.46 |
| ▸ | FAP | Q12884 | 1/20 | 0.46 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.46 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.46 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25698247 | 0.95 | HRH3 (0.54) | ABHD6DAGLAHRH3ALDH1A1TSHR | |
| SCHEMBL23477764 | 0.85 | ABHD6 (0.54) | ABHD6DAGLAHRH3ALDH1A1TSHR | |
| SCHEMBL25698280 | 0.85 | HSD11B1 (0.44) | ABHD6DAGLAKMT2ADAGLBDPP4 | |
| SCHEMBL25698277 | 0.84 | ACACB (0.44) | ABHD6DAGLAALDH1A1KMT2AHPGD | |
| SCHEMBL30360947 | 0.84 | HRH3 (0.54) | ABHD6DAGLAHRH3ALDH1A1DAGLB | |
| SCHEMBL11481440 | 0.83 | HSD11B1 (0.57) | ABHD6DAGLAKMT2ADAGLBDPP4 | |
| SCHEMBL11575911 | 0.83 | HRH3 (0.51) | ABHD6DAGLAHRH3ALDH1A1TSHR | |
| SCHEMBL27651068 | 0.82 | HSD11B1 (0.58) | ABHD6DAGLAKMT2ADAGLBDPP4 | |
| SCHEMBL23458983 | 0.81 | EPHX2 (0.47) | ABHD6DAGLAHRH3ALDH1A1TSHR | |
| SCHEMBL25698244 | 0.80 | ACACB (0.45) | ABHD6DAGLAHRH3KMT2ADPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11685734-B2 | ATM kinase inhibitors and compositions and methods of use thereof | CHDI FOUNDATION, INC. (US) | 2023-06-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11685734-B2 | ATM kinase inhibitors and compositions and methods of use thereof | ATM, CHEK2, CHEK1 | ABHD6 3275/4885DAGLA 3969/4885HRH3 3954/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.