Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.51 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.49 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | DAGLB | Q8NCG7 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | NAPEPLD | Q6IQ20 | 1/20 | 0.44 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.43 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25698281 | 0.83 | ABHD6 (0.52) | HRH3ABHD6DAGLAALDH1A1KMT2A | |
| SCHEMBL30360947 | 0.80 | HRH3 (0.54) | HRH3ABHD6DAGLAALDH1A1HPGD | |
| SCHEMBL25698247 | 0.80 | HRH3 (0.54) | HRH3ABHD6DAGLAALDH1A1KMT2A | |
| SCHEMBL23477764 | 0.79 | ABHD6 (0.54) | HRH3ABHD6DAGLAALDH1A1KMT2A | |
| SCHEMBL14417553 | 0.76 | HSD11B1 (0.55) | HRH3ABHD6DAGLAALDH1A1KMT2A | |
| SCHEMBL23459119 | 0.76 | HSD11B1 (0.55) | HRH3ABHD6DAGLAALDH1A1KMT2A | |
| SCHEMBL23458983 | 0.74 | EPHX2 (0.47) | HRH3ABHD6DAGLAALDH1A1NPC1 | |
| SCHEMBL5630494 | 0.73 | LTA4H (0.59) | ALDH1A1NPC1RAB9AKMT2AHPGD | |
| SCHEMBL5630488 | 0.73 | LTA4H (0.59) | ALDH1A1NPC1RAB9AKMT2AHPGD | |
| SCHEMBL6986064 | 0.73 | HCRTR1 (0.51) | HRH3ABHD6DAGLANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-53147077-A | — | — | None | — | — | JP | disclosed |
| JP-S53147077-A | 2-BENZYLPIPERIDINE DERIVATIVES | DAI ICHI SEIYAKU CO LTD | 1978-12-21 | — | — | JP | disclosed |