Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 4/20 | 0.54 |
| ▸ | TP53 | P04637 | 3/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 5/20 | 0.52 |
| ▸ | NPC1 | O15118 | 4/20 | 0.52 |
| ▸ | PKM | P14618 | 3/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | CASP3 | P42574 | 1/20 | 0.51 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.51 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7022198 | 0.84 | KMT2A (0.64) | KMT2ASMN1; SMN2ALDH1A1LMNATP53 | |
| SCHEMBL16860869 | 0.82 | KMT2A (0.62) | KMT2ASMN1; SMN2ALDH1A1LMNATP53 | |
| Hydrochloric Acid SCHEMBL28888276 | 0.81 | KMT2A (0.60) | KMT2ASMN1; SMN2ALDH1A1LMNATP53 | |
| SCHEMBL25767652 | 0.79 | KMT2A (0.59) | KMT2ASMN1; SMN2ALDH1A1LMNATP53 | |
| SCHEMBL12233592 | 0.79 | KMT2A (0.59) | KMT2ASMN1; SMN2ALDH1A1LMNATP53 | |
| SCHEMBL12510067 | 0.79 | KMT2A (0.59) | KMT2ASMN1; SMN2ALDH1A1LMNATP53 | |
| SCHEMBL24862884 | 0.78 | KMT2A (0.57) | KMT2ASMN1; SMN2ALDH1A1LMNATP53 | |
| SCHEMBL5798843 | 0.78 | RAB9A (0.65) | KMT2ASMN1; SMN2ALDH1A1LMNATP53 | |
| SCHEMBL4011536 | 0.77 | LDHA (0.78) | KMT2ASMN1; SMN2ALDH1A1LMNATP53 | |
| SCHEMBL1133153 | 0.76 | SMN1; SMN2 (0.57) | KMT2ASMN1; SMN2ALDH1A1LMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023091644-A2 | HSD17B13-RELATED DOUBLE STRANDED OLIGONUCLEOTIDE COMPOSITIONS AND METHODS RELATING THERETO | WAVE LIFE SCIENCES LTD. (SG) | 2023-05-25 | — | — | WO | disclosed |