Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.49 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | LDHA | P00338 | 1/20 | 0.48 |
| ▸ | VDR | P11473 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7022198 | 0.81 | KMT2A (0.64) | KMT2ALMNAALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL17210578 | 0.80 | KCNH3 (0.61) | KMT2ASMN1; SMN2TP53RAB9ANPC1 | |
| SCHEMBL25699280 | 0.79 | KMT2A (0.62) | KMT2ALMNAALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL16860869 | 0.79 | KMT2A (0.62) | KMT2ALMNAALDH1A1SMN1; SMN2TP53 | |
| Hydrochloric Acid SCHEMBL28888276 | 0.78 | KMT2A (0.60) | KMT2ALMNAALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL4011536 | 0.78 | LDHA (0.78) | KMT2ALMNAALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL12233592 | 0.77 | KMT2A (0.59) | KMT2ALMNAALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL12510067 | 0.77 | KMT2A (0.59) | KMT2ALMNAALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL10348741 | 0.76 | CA2 (0.57) | KMT2ALMNAPKMTDP1KDM4E | |
| SCHEMBL24862884 | 0.75 | KMT2A (0.57) | KMT2ALMNAALDH1A1SMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230203087-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2023-06-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230203087-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | RNGTT, NSUN2, ALKBH1 | KMT2A 742/4885LMNA 716/4885ALDH1A1 1901/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.