Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | KCNN3 | Q9UGI6 | 1/20 | 0.44 |
| ▸ | AURKA | O14965 | 2/20 | 0.44 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.44 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.44 |
| ▸ | GBA1 | P04062 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.43 |
| ▸ | GLP1R | P43220 | 1/20 | 0.42 |
| ▸ | DHFR | P00374 | 1/20 | 0.42 |
| ▸ | ULK1 | O75385 | 2/20 | 0.42 |
| ▸ | PFKFB3 | Q16875 | 2/20 | 0.41 |
| ▸ | CDK1 | P06493 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2581385 | 0.82 | IGF1R (0.46) | LMNAHDAC6KCNN3ADRA2AADRA2B | |
| SCHEMBL18425012 | 0.76 | ULK1 (0.39) | ULK1 | |
| SCHEMBL22524371 | 0.75 | IRAK4 (0.52) | LMNAHDAC6KCNN3AURKARPS6KB1 | |
| SCHEMBL22524333 | 0.75 | IRAK4 (0.52) | LMNAHDAC6KCNN3AURKARPS6KB1 | |
| SCHEMBL22524356 | 0.75 | IRAK4 (0.52) | LMNAHDAC6KCNN3AURKARPS6KB1 | |
| SCHEMBL1551936 | 0.73 | LMNA (0.51) | LMNAHDAC6KCNN3AURKARPS6KB1 | |
| SCHEMBL1552289 | 0.73 | LMNA (0.51) | LMNAHDAC6KCNN3AURKARPS6KB1 | |
| SCHEMBL3205734 | 0.73 | LMNA (0.51) | LMNAHDAC6KCNN3AURKARPS6KB1 | |
| SCHEMBL22872938 | 0.73 | GBA1 (0.51) | LMNAHDAC6KCNN3AURKARPS6KB1 | |
| SCHEMBL24453716 | 0.73 | AURKA (0.51) | LMNAHDAC6KCNN3AURKARPS6KB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2384322-B1 | PYRIMIDINE DERIVATIVES AND USE THEREOF FOR COMBATING UNDESIRED PLANT GROWTH | BAYER CROPSCIENCE AG (DE) | 2014-08-27 | — | — | EP | disclosed |
| US-8445408-B2 | Pyrimidine derivatives and their use for controlling undesired plant growth | BAYER CROPSCIENCE AG (DE) | 2013-05-21 | — | — | US | disclosed |
| CN-102272107-A | Pyrimidine derivatives and their use for combating undesired vegetation | — | 2011-12-07 | — | — | CN | disclosed |
| EP-2384322-A1 | PYRIMIDINE DERIVATIVES AND THE USE THEREOF FOR COMBATING UNDESIRED PLANT GROWTH | Bayer CropScience AG (DE) | 2011-11-09 | — | — | EP | disclosed |
| EP-2206703-A1 | Pyrimidine derivatives and use thereof for combating undesired plant growth | Bayer CropScience AG (DE) | 2010-07-14 | — | — | EP | disclosed |
| WO-2010076009-A1 | PYRIMIDINE DERIVATIVES AND THE USE THEREOF FOR COMBATING UNDESIRED PLANT GROWTH | BAYER CROPSCIENCE AG (DE) | 2010-07-08 | — | — | WO | disclosed |
| US-20100167935-A1 | Pyrimidine derivatives and their use for controlling undesired plant growth | BAYER CROPSCIENCE AG (DE) | 2010-07-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100167935-A1 | Pyrimidine derivatives and their use for controlling undesired plant growth | TYMS, TYMP, UMPS | LMNA 3792/4885HDAC6 4135/4885KCNN3 4740/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.