SCHEMBL25700403

SCHEMBL25700403

c1ccc(-c2nc(-c3ccccc3)nc(-c3cccc4c3oc3c(-c5ccc6oc7cc(-n8c9ccccc9c9ccccc98)ccc7c6c5)cccc34)n2)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.38
PRKDC P78527 4/20 0.36
PTGER4 P35408 1/20 0.33
GGPS1 O95749 1/20 0.32
PIK3CD O00329 2/20 0.32
PIK3CA P42336 2/20 0.32
PIK3CB P42338 2/20 0.32
PIK3CG P48736 2/20 0.32
CHEK2 O96017 1/20 0.32
PTPRF P10586 4/20 0.31
PTPN2 P17706 4/20 0.31
PTPN1 P18031 4/20 0.31
PRMT5 O14744 1/20 0.31
WDR77 Q9BQA1 1/20 0.31
PLA2G10 O15496 1/20 0.31
PLA2G2A P14555 1/20 0.31
PLA2G4A P47712 1/20 0.31
PTGES2 Q9H7Z7 1/20 0.31
JAK2 O60674 1/20 0.31
JAK1 P23458 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25926357 0.97 ALOX5 (0.41) ALOX5PRKDCGGPS1PIK3CDPIK3CA
SCHEMBL25458348 0.96 ALOX5 (0.36) ALOX5PRKDCPTGER4GGPS1PIK3CD
SCHEMBL24232216 0.96 ALOX5 (0.38) ALOX5PRKDCPTGER4GGPS1PIK3CD
SCHEMBL25926638 0.96 ALOX5 (0.42) ALOX5PRKDCPTGER4GGPS1PIK3CD
SCHEMBL25926590 0.96 ALOX5 (0.42) ALOX5PRKDCPTGER4GGPS1PIK3CD
SCHEMBL25458373 0.95 ALOX5 (0.35) ALOX5PRKDCPTGER4GGPS1PLA2G10
SCHEMBL24217156 0.95 ALOX5 (0.39) ALOX5PRKDCPTGER4GGPS1PIK3CD
SCHEMBL25926376 0.95 ALOX5 (0.37) ALOX5PRKDCPTGER4PIK3CDPIK3CB
SCHEMBL24363375 0.95 ALOX5 (0.39) ALOX5PRKDCPTGER4GGPS1PIK3CD
SCHEMBL25926604 0.95 ALOX5 (0.41) ALOX5PRKDCPTGER4GGPS1PIK3CD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230247902-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME, AND COMPOSITION FOR ORGANIC LAYER OF ORGANIC LIGHT-EMITTING DEVICE LT MATERIALS CO., LTD. (KR) 2023-08-03 US disclosed
US-20230247902-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME, AND COMPOSITION FOR ORGANIC LAYER OF ORGANIC LIGHT-EMITTING DEVICE LT MATERIALS CO., LTD. (KR) 2023-08-03 US disclosed
EP-4190779-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME, AND COMPOSITION FOR ORGANIC LAYER OF ORGANIC LIGHT-EMITTING DEVICE LT Materials Co., Ltd. (KR) 2023-06-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230247902-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME, AND COMPOSITION FOR ORGANIC LAYER OF ORGANIC LIGHT-EMITTING DEVICE CRY1, PPOX, ORC3 ALOX5 959/4885PRKDC 3471/4885PTGER4 2825/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.