Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 5/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | FEN1 | P39748 | 1/20 | 0.51 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.47 |
| ▸ | TNKS | O95271 | 1/20 | 0.47 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.42 |
| ▸ | CCR1 | P32246 | 1/20 | 0.42 |
| ▸ | CCR8 | P51685 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8695674 | 0.82 | BRD4 (0.48) | NQO2KDM4EFEN1TNKSGRM4 | |
| SCHEMBL829613 | 0.81 | TNKS (0.52) | KDM4EFEN1TNKSGRM4CCR1 | |
| SCHEMBL21591678 | 0.81 | FEN1 (0.50) | NQO2KDM4EFEN1TNKSGRM4 | |
| SCHEMBL5871967 | 0.81 | FEN1 (0.54) | KDM4EFEN1TNKSGRM4HPGD | |
| SCHEMBL23443327 | 0.79 | KDM4E (0.45) | KDM4ECCR1CCR8HPGDALDH1A1 | |
| SCHEMBL21593928 | 0.79 | FEN1 (0.48) | NQO2KDM4EFEN1TNKSGRM4 | |
| SCHEMBL13923062 | 0.79 | FEN1 (0.48) | NQO2KDM4EFEN1TNKSGRM4 | |
| SCHEMBL8696587 | 0.78 | HSD17B10 (0.60) | FEN1TNKSGRM4CYP2C19ALDH1A1 | |
| SCHEMBL8695958 | 0.76 | ELANE (0.46) | FEN1TNKS | |
| SCHEMBL830438 | 0.76 | HPGD (0.43) | FEN1TNKSCYP1A2HPGDCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3856737-B1 | HETEROCYCLYL COMPOUNDS FOR THE TREATMENT OF AUTOIMMUNE DISEASE | HOFFMANN LA ROCHE (CH) | 2023-05-17 | — | — | EP | disclosed |
| US-20090054477-A1 | 4-thio substituted quinoline and naphthyridine compounds | PRESIDIO PHARMACEUTICALS, INC. | 2009-02-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090054477-A1 | 4-thio substituted quinoline and naphthyridine compounds | GTF3C4, HNF4A, TENT4A | NQO2 20/4885KDM4E 1265/4885FEN1 2320/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.