Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.60 |
| ▸ | FEN1 | P39748 | 1/20 | 0.47 |
| ▸ | BRD4 | O60885 | 2/20 | 0.45 |
| ▸ | TNKS | O95271 | 1/20 | 0.43 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | CREBBP | Q92793 | 3/20 | 0.42 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.42 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.42 |
| ▸ | PIM1 | P11309 | 1/20 | 0.42 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.42 |
| ▸ | CDK2 | P24941 | 1/20 | 0.42 |
| ▸ | CDK9 | P50750 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8691823 | 0.87 | TNKS (0.52) | HSD17B10FEN1TNKSALDH1A1CYP2C19 | |
| SCHEMBL8695958 | 0.86 | ELANE (0.46) | HSD17B10FEN1TNKS | |
| SCHEMBL8691820 | 0.85 | PIK3CD (0.51) | HSD17B10FEN1TNKSPDE4ACDK2 | |
| SCHEMBL8691107 | 0.85 | BRD4 (0.52) | HSD17B10FEN1BRD4TNKSPIM1 | |
| SCHEMBL8693905 | 0.85 | PDE4A (0.45) | HSD17B10FEN1TNKSALDH1A1PDE4A | |
| SCHEMBL8692400 | 0.85 | TNKS (0.50) | HSD17B10FEN1TNKSCYP2C19PDE4A | |
| SCHEMBL8693990 | 0.84 | TNKS (0.49) | HSD17B10FEN1BRD4TNKSCYP2C19 | |
| SCHEMBL8694011 | 0.83 | BRD4 (0.54) | HSD17B10BRD4PDE4APDE4BPDE4C | |
| SCHEMBL8695674 | 0.82 | BRD4 (0.48) | HSD17B10FEN1BRD4TNKSCREBBP | |
| SCHEMBL8692262 | 0.82 | HSD17B10 (0.47) | HSD17B10BRD4ALDH1A1TSHRCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5817670-A | RESPIRATORY SYSTEM DISORDERS, ORGAN TRANSPLANTATION, ANTITUMOR AGENTS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1998-10-06 | — | — | US | disclosed |
| EP-0779292-A1 | NOVEL NAPHTHYRIDINE DERIVATIVE AND MEDICINAL COMPOSITION THEREOF | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1997-06-18 | — | — | EP | disclosed |