Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 4/20 | 0.48 |
| ▸ | FEN1 | P39748 | 1/20 | 0.44 |
| ▸ | TNKS | O95271 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | NQO2 | P16083 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.40 |
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | CDK9 | P50750 | 1/20 | 0.40 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.40 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.39 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8696587 | 0.82 | HSD17B10 (0.60) | BRD4FEN1TNKSCCNT1PIM1 | |
| SCHEMBL25703950 | 0.82 | NQO2 (0.54) | FEN1TNKSKDM4ENQO2GRM4 | |
| SCHEMBL8692208 | 0.80 | TNKS (0.47) | FEN1TNKSKDM4ECYP3A4CCNT1 | |
| SCHEMBL8695958 | 0.78 | ELANE (0.46) | FEN1TNKSHSD17B10BACE1 | |
| SCHEMBL8691823 | 0.76 | TNKS (0.52) | FEN1TNKSKDM4ECYP3A4HSD17B10 | |
| SCHEMBL8693990 | 0.76 | TNKS (0.49) | BRD4FEN1TNKSCCNT1PIM1 | |
| SCHEMBL829613 | 0.74 | TNKS (0.52) | FEN1TNKSKDM4ECYP3A4GRM4 | |
| SCHEMBL5871967 | 0.74 | FEN1 (0.54) | FEN1TNKSKDM4EHSD17B10GRM4 | |
| SCHEMBL21591678 | 0.74 | FEN1 (0.50) | FEN1TNKSKDM4ENQO2HSD17B10 | |
| SCHEMBL8693905 | 0.74 | PDE4A (0.45) | FEN1TNKSKDM4EHSD17B10BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5817670-A | RESPIRATORY SYSTEM DISORDERS, ORGAN TRANSPLANTATION, ANTITUMOR AGENTS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1998-10-06 | — | — | US | disclosed |
| EP-0779292-A1 | NOVEL NAPHTHYRIDINE DERIVATIVE AND MEDICINAL COMPOSITION THEREOF | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1997-06-18 | — | — | EP | disclosed |