Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 4/20 | 0.46 |
| ▸ | CYCS | P99999 | 3/20 | 0.45 |
| ▸ | TERT | O14746 | 3/20 | 0.44 |
| ▸ | STAT3 | P40763 | 1/20 | 0.43 |
| ▸ | STAT1 | P42224 | 1/20 | 0.43 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16978932 | 0.91 | TOP1 (0.54) | TOP1CYCSTERTSTAT3STAT1 | |
| SCHEMBL25703764 | 0.91 | TOP1 (0.54) | TOP1CYCSTERTSTAT3STAT1 | |
| SCHEMBL16978922 | 0.91 | TOP1 (0.54) | TOP1CYCSTERTSTAT3STAT1 | |
| SCHEMBL10002104 | 0.88 | TOP1 (0.53) | TOP1CYCSTERTSTAT3STAT1 | |
| SCHEMBL18887296 | 0.86 | TOP1 (0.49) | TOP1CYCSTERTSTAT3STAT1 | |
| SCHEMBL1971674 | 0.85 | TERT (0.57) | TOP1CYCSTERTENPP2HDAC6 | |
| SCHEMBL30774963 | 0.85 | TERT (0.57) | TOP1CYCSTERTENPP2HDAC6 | |
| SCHEMBL27949267 | 0.84 | TERT (0.55) | TOP1CYCSTERTENPP2HDAC6 | |
| SCHEMBL16923754 | 0.82 | TOP1 (0.46) | TOP1CYCSTERTSTAT3STAT1 | |
| SCHEMBL19879796 | 0.82 | TOP1 (0.46) | TOP1CYCSTERTSTAT3STAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230192692-A1 | MACROCYCLIC AND CAGE-LIKE MOLECULE BASED ON BIPHEN[n]ARENE AND DERIVATIVE, SYNTHESIS METHOD AND USE THEREOF | TIANJIN NORMAL UNIVERSITY (CN) | 2023-06-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230192692-A1 | MACROCYCLIC AND CAGE-LIKE MOLECULE BASED ON BIPHEN[n]ARENE AND DERIVATIVE, SYNTHESIS METHOD AND USE THEREOF | TPMT, NUDT1, PNP | TOP1 885/4885CYCS 1541/4885TERT 461/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.