Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.46 |
| ▸ | S1PR4 | O95977 | 3/20 | 0.46 |
| ▸ | S1PR5 | Q9H228 | 3/20 | 0.46 |
| ▸ | LPL | P06858 | 2/20 | 0.46 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.46 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.45 |
| ▸ | PPARG | P37231 | 2/20 | 0.43 |
| ▸ | PPARA | Q07869 | 2/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL450142 | 0.88 | ALDH1A1 (0.54) | ALDH1A1CYP3A4HPGDHSD17B10EPHX1 | |
| SCHEMBL160938 | 0.88 | ALDH1A1 (0.54) | ALDH1A1CYP3A4HPGDHSD17B10EPHX1 | |
| SCHEMBL29767685 | 0.88 | LPL (0.56) | S1PR1S1PR4S1PR5LPLLIPG | |
| SCHEMBL11871771 | 0.88 | LPL (0.56) | S1PR1S1PR4S1PR5LPLLIPG | |
| SCHEMBL9418466 | 0.88 | LPL (0.56) | S1PR1S1PR4S1PR5LPLLIPG | |
| SCHEMBL31498428 | 0.87 | ALDH1A1 (0.53) | ALDH1A1CYP3A4HPGDHSD17B10EPHX1 | |
| SCHEMBL24244461 | 0.86 | LPL (0.51) | ALDH1A1S1PR1S1PR4S1PR5LPL | |
| SCHEMBL20921417 | 0.86 | LPL (0.51) | ALDH1A1S1PR1S1PR4S1PR5LPL | |
| SCHEMBL31498429 | 0.85 | HSD17B10 (0.54) | ALDH1A1CYP3A4HPGDHSD17B10NPC1 | |
| SCHEMBL10106218 | 0.85 | LPL (0.50) | ALDH1A1S1PR1S1PR4S1PR5LPL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2382289-A1 | ANTI-WEAR AGENT AND LUBRICATING COMPOSITION WITH SUPERIOR ANTI-WEAR PROPERTIES CONTAINING SAME | Shell Internationale Research Maatschappij B.V. (NL) | 2011-11-02 | — | — | EP | disclosed |
| WO-2010086357-A1 | ANTI-WEAR AGENT AND LUBRICATING COMPOSITION WITH SUPERIOR ANTI-WEAR PROPERTIES CONTAINING SAME | SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) | 2010-08-05 | — | — | WO | disclosed |