SCHEMBL450142

SCHEMBL450142

CCCCCCCCCCCCc1ccc(Nc2ccc3ccccc3c2)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.54
CYP3A4 P08684 2/20 0.54
HSD17B10 Q99714 2/20 0.54
HPGD P15428 2/20 0.54
LMNA P02545 3/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
NPC1 O15118 1/20 0.50
RAB9A P51151 1/20 0.50
EPHX1 P07099 1/20 0.50
UNG P13051 3/20 0.49
BCHE P06276 2/20 0.48
TRPV1 Q8NER1 4/20 0.47
ESR1 P03372 2/20 0.45
ADRA2A P08913 2/20 0.45
ADORA3 P0DMS8 2/20 0.45
TACR2 P21452 2/20 0.45
SLC6A2 P23975 2/20 0.45
SLC6A4 P31645 2/20 0.45
SLC6A3 Q01959 2/20 0.45
KDM4E B2RXH2 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL160938 1.00 ALDH1A1 (0.54) ALDH1A1CYP3A4HSD17B10HPGDLMNA
SCHEMBL3925384 0.93 ALDH1A1 (0.47) ALDH1A1CYP3A4HSD17B10HPGDLMNA
SCHEMBL31498428 0.90 ALDH1A1 (0.53) ALDH1A1CYP3A4HSD17B10HPGDLMNA
SCHEMBL2570534 0.88 ALDH1A1 (0.51) ALDH1A1CYP3A4HSD17B10HPGDLMNA
SCHEMBL31498429 0.88 HSD17B10 (0.54) ALDH1A1CYP3A4HSD17B10HPGDLMNA
SCHEMBL1423027 0.84 UNG (0.54) ALDH1A1CYP3A4HSD17B10LMNAUNG
SCHEMBL11204938 0.84 HTR2A (0.54) ALDH1A1CYP3A4HSD17B10LMNAUNG
SCHEMBL21634393 0.84 HTR2A (0.54) ALDH1A1CYP3A4HSD17B10LMNAUNG
SCHEMBL449939 0.84 HTR2A (0.54) ALDH1A1CYP3A4HSD17B10LMNAUNG
SCHEMBL27480376 0.84 HTR2A (0.54) ALDH1A1CYP3A4HSD17B10LMNAUNG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 394 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3410034-B1 REFRIGERATION DEVICE DAIKIN IND LTD (JP) 2022-11-23 EP claimed
US-11352532-B2 Refrigeration apparatus DAIKIN INDUSTRIES, LTD. (JP) 2022-06-07 US claimed
US-11085677-B2 Refrigerant recovery device and refrigerant recovery method DAIKIN INDUSTRIES, LTD. (JP) 2021-08-10 US claimed
US-20200385618-A1 REFRIGERATION APPARATUS DAIKIN INDUSTRIES, LTD. (JP) 2020-12-10 US claimed
US-10851275-B2 Refrigeration apparatus DAIKIN INDUSTRIES, LTD. (JP) 2020-12-01 US claimed
US-10550351-B2 Refrigerator oil and refrigerator working fluid composition JX NIPPON OIL & ENERGY CORPORATION (JP) 2020-02-04 US claimed
US-20190048240-A1 REFRIGERATION APPARATUS DAIKIN INDUSTRIES, LTD. (JP) 2019-02-14 US claimed
US-20190032976-A1 REFRIGERANT RECOVERY DEVICE AND REFRIGERANT RECOVERY METHOD DAIKIN INDUSTRIES, LTD. (JP) 2019-01-31 US claimed
EP-3410034-A1 REFRIGERATION DEVICE Daikin Industries, Ltd. (JP) 2018-12-05 EP claimed
EP-3410040-A1 REFRIGERANT RECOVERY DEVICE AND REFRIGERANT RECOVERY METHOD Daikin Industries, Ltd. (JP) 2018-12-05 EP claimed
EP-1969607-A1 A COMPOSITION OF INSULATING FLUID AND PROCESS FOR THE PREPARATION THEREOF COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2008-09-17 EP claimed
EP-1963467-A1 A COMPOSITION OF HYDRAULIC FLUID AND PROCESS FOR THE PREPARETION THEREOF Council of Scientific & Industrial Research (IN) 2008-09-03 EP claimed
WO-2007089645-A2 BIODIESEL FUEL ADDITIVE ORYXE ENERGY INTERNATIONAL, INC. (US) 2007-08-09 WO claimed
WO-2007066348-A1 A COMPOSITION OF LUBRICATING OIL FOR TWO STROKE GASOLINE ENGINE AND PROCESS FOR THE PREPARATION THEREOF COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2007-06-14 WO claimed
WO-2007066347-A1 A COMPOSITION OF INSULATING FLUID AND PROCESS FOR THE PREPARATION THEREOF COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2007-06-14 WO claimed
WO-2007066349-A1 A COMPOSITION OF HYDRAULIC FLUID AND PROCESS FOR THE PREPARETION THEREOF COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2007-06-14 WO claimed
US-20070135318-A1 Composition of lubricating oil for two stroke gasoline engine and process for the preparation thereof COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH 2007-06-14 US claimed
US-20070060486-A1 Composition of hydraulic fluid and process for the preparation thereof COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2007-03-15 US claimed
US-20070060484-A1 Composition of insulating fluid and process for the preparation thereof COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2007-03-15 US claimed
US-20060201056-A1 Biodiesel fuel additive ORYXE ENERGY INTERNATIONAL, INC. (US) 2006-09-14 US claimed