Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.50 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.43 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.43 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.43 |
| ▸ | CDK2 | P24941 | 1/20 | 0.43 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.43 |
| ▸ | CDK1 | P06493 | 1/20 | 0.43 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.43 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.43 |
| ▸ | CLK1 | P49759 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25243808 | 0.87 | CDK1 (0.46) | THRBCHRM4NPC1GAAMAPT | |
| SCHEMBL30566199 | 0.87 | CDK1 (0.46) | THRBCHRM4NPC1GAAMAPT | |
| SCHEMBL25804261 | 0.86 | THRB (0.48) | THRBCHRM4NPC1CACNA2D1TP53 | |
| SCHEMBL30446331 | 0.77 | CDK1 (0.46) | THRBCHRM4NPC1GAAMAPT | |
| SCHEMBL25273214 | 0.77 | CDK1 (0.46) | THRBCHRM4NPC1GAAMAPT | |
| SCHEMBL25283284 | 0.75 | CDK1 (0.49) | THRBNPC1TP53LMNACLK4 | |
| SCHEMBL30566240 | 0.75 | CDK1 (0.49) | THRBNPC1TP53LMNACLK4 | |
| SCHEMBL25804253 | 0.75 | THRB (0.52) | THRBCHRM4NPC1CACNA2D1MAPT | |
| SCHEMBL19961228 | 0.72 | CCNE2 (0.47) | THRBCHRM4NPC1GAAMAPT | |
| SCHEMBL13201559 | 0.72 | TP53 (0.47) | THRBNPC1GAAMAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023115142-A1 | ARYLSULPHONAMIDE COMPOUNDS | Anaxis Pharma Pty Ltd (AU) | 2023-06-29 | — | — | WO | disclosed |