Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | CDK1 | P06493 | 3/20 | 0.47 |
| ▸ | CCNB2 | O95067 | 2/20 | 0.47 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.47 |
| ▸ | CCNB3 | Q8WWL7 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | PDE1A | P54750 | 2/20 | 0.45 |
| ▸ | PDE1B | Q01064 | 2/20 | 0.45 |
| ▸ | PDE1C | Q14123 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.42 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.42 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.42 |
| ▸ | PDE5A | O76074 | 1/20 | 0.42 |
| ▸ | PDE6C | P51160 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30566240 | 0.87 | CDK1 (0.49) | THRBCDK1CCNB2CCNB1CCNB3 | |
| SCHEMBL25283284 | 0.87 | CDK1 (0.49) | THRBCDK1CCNB2CCNB1CCNB3 | |
| SCHEMBL25706604 | 0.86 | THRB (0.50) | THRBCDK1CCNB2CCNB1CCNB3 | |
| SCHEMBL30577105 | 0.76 | PDE1A (0.60) | CDK1CCNB2CCNB1CCNB3PDE1A | |
| SCHEMBL25243808 | 0.75 | CDK1 (0.46) | THRBCDK1CCNB2CCNB1CCNB3 | |
| SCHEMBL30566199 | 0.75 | CDK1 (0.46) | THRBCDK1CCNB2CCNB1CCNB3 | |
| SCHEMBL25804253 | 0.73 | THRB (0.52) | THRBCDK1CCNB2CCNB1CCNB3 | |
| SCHEMBL25273214 | 0.73 | CDK1 (0.46) | THRBCDK1CCNB2CCNB1CCNB3 | |
| SCHEMBL30446331 | 0.73 | CDK1 (0.46) | THRBCDK1CCNB2CCNB1CCNB3 | |
| SCHEMBL22581153 | 0.72 | CYP1A2 (0.46) | TDP1NPC1LMNATP53CLK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023115150-A1 | BIFUNCTIONAL ARYLSULPHONAMIDE COMPOUNDS | Anaxis Pharma Pty Ltd (AU) | 2023-06-29 | — | — | WO | disclosed |