Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B10 | O60218 | 12/20 | 0.77 |
| ▸ | AKR1B1 | P15121 | 11/20 | 0.77 |
| ▸ | AKR1A1 | P14550 | 2/20 | 0.67 |
| ▸ | CBR1 | P16152 | 2/20 | 0.67 |
| ▸ | AKR1C4 | P17516 | 2/20 | 0.67 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.67 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.67 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.67 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | CA12 | O43570 | 2/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | CA4 | P22748 | 2/20 | 0.50 |
| ▸ | CA5A | P35218 | 2/20 | 0.50 |
| ▸ | CA7 | P43166 | 2/20 | 0.50 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25279702 | 0.99 | AKR1B10 (0.75) | AKR1B10AKR1B1AKR1A1CBR1AKR1C4 | |
| SCHEMBL25235579 | 0.92 | AKR1B10 (0.64) | AKR1B10AKR1B1AKR1A1CBR1AKR1C4 | |
| SCHEMBL25239509 | 0.89 | AKR1B10 (0.60) | AKR1B10AKR1B1AKR1A1CBR1AKR1C4 | |
| SCHEMBL43817 | 0.88 | AKR1B10 (0.59) | AKR1B10AKR1B1AKR1A1CBR1AKR1C4 | |
| SCHEMBL25710676 | 0.83 | AKR1B10 (0.56) | AKR1B10AKR1B1AKR1A1CBR1AKR1C4 | |
| SCHEMBL25508901 | 0.81 | AKR1B10 (0.64) | AKR1B10AKR1B1AKR1A1CBR1AKR1C4 | |
| SCHEMBL13534005 | 0.80 | AKR1B10 (0.63) | AKR1B10AKR1B1AKR1A1CBR1AKR1C4 | |
| Trifluoroacetic Acid SCHEMBL21806629 | 0.80 | AKR1B10 (0.49) | AKR1B10AKR1B1AKR1A1CBR1AKR1C4 | |
| SCHEMBL25508898 | 0.79 | AKR1B10 (0.61) | AKR1B10AKR1B1AKR1A1CBR1AKR1C4 | |
| SCHEMBL25508896 | 0.79 | AKR1B10 (0.60) | AKR1B10AKR1B1AKR1A1CBR1AKR1C4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230192658-A1 | CONJUGATES INCLUDING A DETECTABLE MOIETY | VENTANA MEDICAL SYSTEMS, INC. | 2023-06-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230192658-A1 | CONJUGATES INCLUDING A DETECTABLE MOIETY | CD2BP2, CD47, CD44 | AKR1B10 1579/4885AKR1B1 1876/4885AKR1A1 2149/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.