Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B10 | O60218 | 10/20 | 0.63 |
| ▸ | AKR1B1 | P15121 | 10/20 | 0.63 |
| ▸ | AKR1A1 | P14550 | 2/20 | 0.60 |
| ▸ | CBR1 | P16152 | 2/20 | 0.60 |
| ▸ | AKR1C4 | P17516 | 2/20 | 0.60 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.60 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.60 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | MIF | P14174 | 3/20 | 0.57 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25508901 | 0.92 | AKR1B10 (0.64) | AKR1B10AKR1B1AKR1A1CBR1AKR1C4 | |
| SCHEMBL25508898 | 0.88 | AKR1B10 (0.61) | AKR1B10AKR1B1AKR1A1CBR1AKR1C4 | |
| SCHEMBL25508896 | 0.87 | AKR1B10 (0.60) | AKR1B10AKR1B1AKR1A1CBR1AKR1C4 | |
| SCHEMBL25279702 | 0.81 | AKR1B10 (0.75) | AKR1B10AKR1B1AKR1A1CBR1AKR1C4 | |
| SCHEMBL11073365 | 0.80 | AKR1B10 (0.74) | AKR1B10AKR1B1AKR1A1CBR1AKR1C4 | |
| SCHEMBL22800560 | 0.80 | AKR1B10 (0.70) | AKR1B10AKR1B1AKR1A1CBR1AKR1C4 | |
| SCHEMBL21806228 | 0.80 | AKR1B10 (0.59) | AKR1B10AKR1B1AKR1A1CBR1AKR1C4 | |
| SCHEMBL25708668 | 0.80 | AKR1B10 (0.77) | AKR1B10AKR1B1AKR1A1CBR1AKR1C4 | |
| SCHEMBL23636551 | 0.80 | ALDH1A1 (0.56) | AKR1B10AKR1B1KDM4EMEN1KMT2A | |
| SCHEMBL23960027 | 0.79 | AKR1B10 (0.68) | AKR1B10AKR1B1AKR1A1CBR1AKR1C4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8852640-B2 | Micelles for delivery of nitric oxide | ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) (CH) | 2014-10-07 | — | — | US | disclosed |
| US-20100003338-A1 | Micelles for delivery of nitric oxide | ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) (CH) | 2010-01-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100003338-A1 | Micelles for delivery of nitric oxide | NOS2, NOS1, NOS3 | AKR1B10 782/4885AKR1B1 742/4885AKR1A1 901/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.