Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.40 |
| ▸ | RXRA | P19793 | 6/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 6/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 6/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
| ▸ | PLK1 | P53350 | 1/20 | 0.34 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.33 |
| ▸ | ESRRA | P11474 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MDM4 | O15151 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12545834 | 0.82 | DRD2 (0.46) | DRD2DRD3KCNH2NOTUMGRM2 | |
| SCHEMBL17721655 | 0.77 | MAPT (0.47) | DRD2DRD3KCNH2ALDH1A1CYP3A4 | |
| SCHEMBL16786522 | 0.75 | DRD2 (0.50) | DRD2DRD3KCNH2NOTUMRXRA | |
| SCHEMBL10224168 | 0.74 | DRD2 (0.47) | DRD2DRD3KCNH2NOTUMGRM2 | |
| SCHEMBL11994562 | 0.74 | PARP1 (0.34) | DRD2ALDH1A1TP53CYP3A4MAPT | |
| SCHEMBL19701984 | 0.71 | PIK3CD (0.47) | DRD2DRD3KCNH2NOTUMGRM2 | |
| SCHEMBL276758 | 0.71 | LMNA (0.53) | NOTUMHRH3KDM4EALDH1A1TP53 | |
| SCHEMBL16019525 | 0.71 | NOTUM (0.56) | DRD2DRD3KCNH2NOTUMHRH3 | |
| SCHEMBL10224195 | 0.71 | NOTUM (0.47) | DRD2DRD3KCNH2NOTUMGRM2 | |
| SCHEMBL22797019 | 0.70 | DRD2 (0.49) | DRD2DRD3KCNH2NOTUMGRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3752498-B1 | SOMATOSTATIN MODULATORS AND USES THEREOF | CRINETICS PHARMACEUTICALS INC (US) | 2023-06-28 | — | — | EP | disclosed |