Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 1/20 | 0.30 |
| ▸ | METAP1 | P53582 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18175928 | 0.87 | — | — | |
| SCHEMBL25710427 | 0.78 | — | — | |
| SCHEMBL2550728 | 0.72 | — | — | |
| SCHEMBL24287227 | 0.69 | — | — | |
| SCHEMBL13302739 | 0.69 | — | — | |
| SCHEMBL24311674 | 0.68 | NOS2 (0.33) | — | |
| SCHEMBL24311808 | 0.68 | NOS2 (0.33) | — | |
| SCHEMBL14151192 | 0.67 | — | — | |
| SCHEMBL20077224 | 0.67 | KIF11 (0.38) | — | |
| SCHEMBL13740673 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230183292-A1 | IMMUNOMODULATORS | BRISTOL MYERS SQUIBB CO (US) | 2023-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230183292-A1 | IMMUNOMODULATORS | CD274, PDCD1LG2, PDCD1 | METAP2 2506/4885METAP1 1723/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.