⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25710213 | 0.87 | METAP2 (0.30) | — | |
| SCHEMBL25710427 | 0.76 | — | — | |
| SCHEMBL24311674 | 0.71 | NOS2 (0.33) | — | |
| SCHEMBL15795237 | 0.71 | ARG1 (0.50) | — | |
| SCHEMBL24311808 | 0.71 | NOS2 (0.33) | — | |
| SCHEMBL2550728 | 0.70 | — | — | |
| SCHEMBL20077224 | 0.70 | KIF11 (0.38) | — | |
| SCHEMBL13740673 | 0.68 | — | — | |
| SCHEMBL24153955 | 0.66 | TDP1 (0.37) | — | |
| SCHEMBL24153950 | 0.66 | ALDH1A1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3085388-A1 | HYPERBRANCHED POLYMER CONJUGATES VIA NON-ENZYMATIC CLEAVABLE LINKER | Ascendis Pharma Growth Disorders Division A/S (DK) | 2016-10-26 | — | — | EP | disclosed |