Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 15/20 | 0.60 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24053768 | 0.95 | RIPK1 (0.56) | RIPK1HRH3KCNH2 | |
| SCHEMBL25713497 | 0.88 | RIPK1 (0.55) | RIPK1HRH3KCNH2ALDH1A1 | |
| SCHEMBL23830897 | 0.86 | ALDH1A1 (0.63) | RIPK1ALDH1A1 | |
| SCHEMBL23830754 | 0.85 | RIPK1 (0.64) | RIPK1ALDH1A1 | |
| SCHEMBL23830983 | 0.85 | RIPK1 (0.64) | RIPK1ALDH1A1 | |
| SCHEMBL24054237 | 0.83 | RIPK1 (0.50) | RIPK1HRH3KCNH2 | |
| SCHEMBL23830888 | 0.81 | RIPK1 (0.70) | RIPK1 | |
| SCHEMBL23830584 | 0.81 | RIPK1 (0.69) | RIPK1 | |
| SCHEMBL25694235 | 0.81 | RIPK1 (0.67) | RIPK1 | |
| SCHEMBL23831039 | 0.80 | RIPK1 (0.72) | RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230203019-A1 | Piperazine Cyclic Ureas | SIRONAX (BEIJING) CO., LTD. (CN) | 2023-06-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230203019-A1 | Piperazine Cyclic Ureas | RIPK1, RIPK3, RIPK4 | RIPK1 1/4885HRH3 1200/4885KCNH2 3782/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.