Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | BTK | Q06187 | 3/20 | 0.33 |
| ▸ | RYR2 | Q92736 | 1/20 | 0.33 |
| ▸ | JAK3 | P52333 | 3/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
| ▸ | TACR3 | P29371 | 2/20 | 0.31 |
| ▸ | TET3 | O43151 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | FBXL19 | Q6PCT2 | 1/20 | 0.31 |
| ▸ | CXXC5 | Q7LFL8 | 1/20 | 0.31 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.31 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.31 |
| ▸ | CXXC4 | Q9H2H0 | 1/20 | 0.31 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25976628 | 0.72 | NOTUM (0.40) | MAPK1ACHEBTKRYR2JAK3 | |
| SCHEMBL25976627 | 0.71 | P2RX7 (0.53) | MAPK1ACHEBTKRYR2JAK3 | |
| SCHEMBL31065977 | 0.68 | TSHR (0.38) | HTTTSHRP2RX7TACR3CYP1A2 | |
| SCHEMBL19042592 | 0.67 | DPP4 (0.51) | — | |
| SCHEMBL25976602 | 0.66 | MAPK1 (0.50) | MAPK1ACHEBTKRYR2EGFR | |
| SCHEMBL25976625 | 0.66 | MAPK1 (0.38) | MAPK1ACHEBTKRYR2TET3 | |
| SCHEMBL24639555 | 0.66 | POLB (0.38) | MAPK1TSHRBTKJAK3P2RX7 | |
| SCHEMBL12764449 | 0.64 | TET3 (0.47) | MAPK1ACHETSHRJAK3TET3 | |
| SCHEMBL167151 | 0.64 | TET3 (0.47) | MAPK1ACHETSHRJAK3TET3 | |
| SCHEMBL20547259 | 0.64 | TET3 (0.47) | MAPK1ACHETSHRJAK3TET3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023104035-A1 | SUBSTITUTED MONOCYCLIC OR BICYCLIC HETEROCYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF | 英矽智能科技(上海)有限公司 | 2023-06-15 | — | — | WO | disclosed |