Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 3/20 | 0.55 |
| ▸ | ABL1 | P00519 | 15/20 | 0.48 |
| ▸ | BCR | P11274 | 15/20 | 0.48 |
| ▸ | TGM2 | P21980 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | SRC | P12931 | 1/20 | 0.43 |
| ▸ | BLK | P51451 | 1/20 | 0.43 |
| ▸ | ITK | Q08881 | 1/20 | 0.43 |
| ▸ | FLT3 | P36888 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25715174 | 0.82 | KDR (0.45) | BTKABL1EGFRSRCBLK | |
| SCHEMBL25714929 | 0.78 | KIT (0.51) | BTKEGFRSRCBLKFLT3 | |
| SCHEMBL22676597 | 0.78 | EGFR (0.50) | BTKTGM2EGFRSRCBLK | |
| SCHEMBL30303260 | 0.78 | EGFR (0.50) | BTKTGM2EGFRSRCBLK | |
| SCHEMBL25718087 | 0.77 | TGM2 (0.46) | BTKTGM2EGFRSRCBLK | |
| SCHEMBL24773365 | 0.76 | BTK (0.54) | BTKTGM2EGFRSRCBLK | |
| SCHEMBL22138109 | 0.76 | TGM2 (0.72) | BTKTGM2EGFRSRCBLK | |
| SCHEMBL29265780 | 0.75 | FGFR1 (0.56) | BTKTGM2EGFRSRCBLK | |
| SCHEMBL25715122 | 0.75 | BTK (0.49) | BTKABL1TGM2EGFRSRC | |
| SCHEMBL22676808 | 0.75 | BTK (0.49) | BTKTGM2EGFRSRCBLK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023104035-A1 | SUBSTITUTED MONOCYCLIC OR BICYCLIC HETEROCYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF | 英矽智能科技(上海)有限公司 | 2023-06-15 | — | — | WO | disclosed |