Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNK2 | Q07912 | 10/20 | 0.41 |
| ▸ | ACVRL1 | P37023 | 6/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.37 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25715608 | 0.84 | TNK2 (0.39) | TNK2ACVRL1 | |
| SCHEMBL25714867 | 0.79 | MAP4K4 (0.40) | TNK2MAP4K4 | |
| SCHEMBL25714868 | 0.79 | KDR (0.39) | TNK2MAP4K4 | |
| SCHEMBL25715553 | 0.78 | CYP11B1 (0.45) | TNK2ACVRL1 | |
| SCHEMBL25715652 | 0.77 | FGFR1 (0.35) | TNK2MAP4K4 | |
| SCHEMBL25715484 | 0.72 | ALOX5AP (0.46) | TNK2ACVRL1 | |
| SCHEMBL25716096 | 0.70 | TEK (0.53) | MAP4K4KMT2A | |
| SCHEMBL25715682 | 0.68 | PIK3CD (0.48) | TNK2ACVRL1 | |
| SCHEMBL31649505 | 0.68 | TNK2 (0.51) | TNK2ACVRL1KMT2A | |
| SCHEMBL22658711 | 0.68 | FGFR1 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023104035-A1 | SUBSTITUTED MONOCYCLIC OR BICYCLIC HETEROCYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF | 英矽智能科技(上海)有限公司 | 2023-06-15 | — | — | WO | disclosed |