Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 7/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.43 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.43 |
| ▸ | CCNC | P24863 | 1/20 | 0.43 |
| ▸ | CDK8 | P49336 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ACVRL1 | P37023 | 2/20 | 0.42 |
| ▸ | BTK | Q06187 | 1/20 | 0.42 |
| ▸ | GSK3A | P49840 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | BCR | P11274 | 1/20 | 0.41 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25715683 | 0.78 | HPGD (0.43) | PIK3CDHPGDKCNH2CSNK2A2CSNK2A1 | |
| SCHEMBL25715685 | 0.78 | PIK3CD (0.43) | PIK3CDHPGDKCNH2CSNK2A2CSNK2A1 | |
| SCHEMBL25715746 | 0.77 | PIK3CD (0.40) | PIK3CDCSNK2A2CSNK2A1ACVRL1TNK2 | |
| SCHEMBL25715553 | 0.72 | CYP11B1 (0.45) | ACVRL1ABL1TNK2 | |
| SCHEMBL30046405 | 0.71 | BTK (0.60) | HPGDKCNH2CCNCCDK8BTK | |
| SCHEMBL25714866 | 0.68 | TNK2 (0.41) | ACVRL1TNK2 | |
| SCHEMBL22676167 | 0.68 | ATR (0.41) | PIK3CDHPGDCCNCCDK8BTK | |
| SCHEMBL27025879 | 0.68 | MET (0.48) | CCNCCDK8BTK | |
| SCHEMBL22676439 | 0.67 | ATR (0.41) | PIK3CDHPGDCCNCCDK8BTK | |
| SCHEMBL60270 | 0.66 | ACVRL1 (0.50) | PIK3CDACVRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023104035-A1 | SUBSTITUTED MONOCYCLIC OR BICYCLIC HETEROCYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF | 英矽智能科技(上海)有限公司 | 2023-06-15 | — | — | WO | disclosed |