Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 5/20 | 0.35 |
| ▸ | FLT3 | P36888 | 3/20 | 0.35 |
| ▸ | LCK | P06239 | 5/20 | 0.34 |
| ▸ | TEK | Q02763 | 3/20 | 0.34 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
| ▸ | NUDT14 | O95848 | 1/20 | 0.33 |
| ▸ | NUDT5 | Q9UKK9 | 1/20 | 0.33 |
| ▸ | CSF1R | P07333 | 2/20 | 0.33 |
| ▸ | KIT | P10721 | 2/20 | 0.33 |
| ▸ | FLT1 | P17948 | 2/20 | 0.33 |
| ▸ | FLT4 | P35916 | 2/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.32 |
| ▸ | PLK4 | O00444 | 1/20 | 0.32 |
| ▸ | AURKA | O14965 | 1/20 | 0.32 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.32 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.32 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.32 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25715020 | 0.83 | FLT3 (0.43) | KDRFLT3LCKCSF1RKIT | |
| SCHEMBL4797665 | 0.74 | ALDH1A1 (0.49) | MAP4K4NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL28981125 | 0.72 | TGFBR1 (0.41) | KDRLCKTEKTGFBR1MAPK14 | |
| SCHEMBL422378 | 0.69 | KDR (0.56) | KDRFLT3LCKMAPK14CSF1R | |
| SCHEMBL28981120 | 0.69 | TGFBR1 (0.34) | KDRLCKTEKTGFBR1MAPK14 | |
| SCHEMBL25716096 | 0.68 | TEK (0.53) | KDRFLT3LCKTEKCSF1R | |
| SCHEMBL25715990 | 0.68 | TNK2 (0.51) | BTKTNK2 | |
| SCHEMBL25715015 | 0.67 | KDR (0.38) | KDRFLT3LCKCSF1RKIT | |
| SCHEMBL25716098 | 0.67 | LCK (0.45) | KDRLCKTEKNUDT14NUDT5 | |
| SCHEMBL25714868 | 0.67 | KDR (0.39) | KDRFLT3LCKTEKCSF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023104035-A1 | SUBSTITUTED MONOCYCLIC OR BICYCLIC HETEROCYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF | 英矽智能科技(上海)有限公司 | 2023-06-15 | — | — | WO | disclosed |