Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 5/20 | 0.49 |
| ▸ | KIT | P10721 | 14/20 | 0.45 |
| ▸ | FLT3 | P36888 | 13/20 | 0.45 |
| ▸ | KDR | P35968 | 13/20 | 0.45 |
| ▸ | CSF1R | P07333 | 6/20 | 0.43 |
| ▸ | FLT1 | P17948 | 6/20 | 0.43 |
| ▸ | FLT4 | P35916 | 6/20 | 0.43 |
| ▸ | LCK | P06239 | 5/20 | 0.43 |
| ▸ | PLK4 | O00444 | 3/20 | 0.43 |
| ▸ | AURKA | O14965 | 3/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.43 |
| ▸ | INSR | P06213 | 3/20 | 0.43 |
| ▸ | MET | P08581 | 3/20 | 0.43 |
| ▸ | FGFR1 | P11362 | 3/20 | 0.43 |
| ▸ | PRKACA | P17612 | 3/20 | 0.43 |
| ▸ | RPS6KB1 | P23443 | 3/20 | 0.43 |
| ▸ | CSNK1D | P48730 | 3/20 | 0.43 |
| ▸ | STK3 | Q13188 | 3/20 | 0.43 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.43 |
| ▸ | NTRK2 | Q16620 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25716316 | 0.90 | EPHB4 (0.40) | BTKKITFLT3KDRCSF1R | |
| SCHEMBL25716849 | 0.88 | KIT (0.44) | KITFLT3KDRCSF1RFLT1 | |
| SCHEMBL25718339 | 0.88 | KDR (0.44) | BTKKITFLT3KDRCSF1R | |
| SCHEMBL25714979 | 0.86 | BTK (0.46) | BTKKITFLT3KDRCSF1R | |
| SCHEMBL25715151 | 0.85 | BTK (0.40) | BTKKITFLT3KDRCSF1R | |
| SCHEMBL25715122 | 0.84 | BTK (0.49) | BTKKITFLT3KDRCSF1R | |
| SCHEMBL25715020 | 0.83 | FLT3 (0.43) | BTKKITFLT3KDRCSF1R | |
| SCHEMBL22676740 | 0.80 | BTK (0.49) | BTKEGFRKCNH2MAP2K7 | |
| SCHEMBL30303325 | 0.80 | BTK (0.49) | BTKEGFRKCNH2MAP2K7 | |
| SCHEMBL25715068 | 0.80 | BTK (0.41) | BTKFLT3KDREGFRKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023104035-A1 | SUBSTITUTED MONOCYCLIC OR BICYCLIC HETEROCYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF | 英矽智能科技(上海)有限公司 | 2023-06-15 | — | — | WO | disclosed |