Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIT | P10721 | 20/20 | 0.44 |
| ▸ | FLT3 | P36888 | 19/20 | 0.44 |
| ▸ | KDR | P35968 | 19/20 | 0.44 |
| ▸ | CSF1R | P07333 | 8/20 | 0.43 |
| ▸ | FLT1 | P17948 | 8/20 | 0.43 |
| ▸ | FLT4 | P35916 | 8/20 | 0.43 |
| ▸ | LCK | P06239 | 7/20 | 0.43 |
| ▸ | LYN | P07948 | 7/20 | 0.43 |
| ▸ | SRC | P12931 | 7/20 | 0.43 |
| ▸ | BLK | P51451 | 7/20 | 0.43 |
| ▸ | FYN | P06241 | 5/20 | 0.43 |
| ▸ | CDK19 | Q9BWU1 | 3/20 | 0.42 |
| ▸ | PLK4 | O00444 | 3/20 | 0.42 |
| ▸ | AURKA | O14965 | 3/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.42 |
| ▸ | INSR | P06213 | 3/20 | 0.42 |
| ▸ | MET | P08581 | 3/20 | 0.42 |
| ▸ | FGFR1 | P11362 | 3/20 | 0.42 |
| ▸ | PRKACA | P17612 | 3/20 | 0.42 |
| ▸ | RPS6KB1 | P23443 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25715071 | 0.88 | BTK (0.49) | KITFLT3KDRCSF1RFLT1 | |
| SCHEMBL25718199 | 0.80 | F10 (0.34) | KDRFGFR1JAK3FGFR2FGFR4 | |
| SCHEMBL25716316 | 0.79 | EPHB4 (0.40) | KITFLT3KDRCSF1RFLT1 | |
| SCHEMBL25718339 | 0.79 | KDR (0.44) | KITFLT3KDRCSF1RFLT1 | |
| SCHEMBL25716265 | 0.76 | KDR (0.38) | KITFLT3KDRCSF1RFLT1 | |
| SCHEMBL25715151 | 0.76 | BTK (0.40) | KITFLT3KDRCSF1RFLT1 | |
| SCHEMBL25714979 | 0.74 | BTK (0.46) | KITFLT3KDRCSF1RFLT1 | |
| SCHEMBL25716910 | 0.73 | KDR (0.46) | KITFLT3KDRCSF1RFLT1 | |
| SCHEMBL30366502 | 0.73 | CYP3A4 (0.42) | KITKDRAURKAFGFR1AURKB | |
| SCHEMBL22676043 | 0.73 | CYP3A4 (0.44) | KITKDRFGFR1JAK3EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023104035-A1 | SUBSTITUTED MONOCYCLIC OR BICYCLIC HETEROCYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF | 英矽智能科技(上海)有限公司 | 2023-06-15 | — | — | WO | disclosed |