SCHEMBL25715211 — predicted protein targets

Predicted protein targets (top 18)

	gene	UniProt	supporting neighbours	confidence
▸	LCK	P06239	2/20	0.36

▸	FYN	P06241	2/20	0.36

▸	CSF1R	P07333	2/20	0.36

▸	LYN	P07948	2/20	0.36

▸	KIT	P10721	2/20	0.36

▸	SRC	P12931	2/20	0.36

▸	FLT1	P17948	2/20	0.36

▸	FLT4	P35916	2/20	0.36

▸	KDR	P35968	2/20	0.36

▸	FLT3	P36888	2/20	0.36

▸	BLK	P51451	2/20	0.36

▸	BTK	Q06187	13/20	0.35

▸	EGFR	P00533	4/20	0.34

▸	KCNH2	Q12809	1/20	0.34

▸	ABL1	P00519	1/20	0.34

▸	GCK	P35557	2/20	0.33

▸	MAPK1	P28482	2/20	0.32

▸	GSTO1	P78417	1/20	0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL25715238	0.90	LCK (0.34)	LCKFYNCSF1RLYNKIT
SCHEMBL25716441	0.88	LCK (0.36)	LCKFYNCSF1RLYNKIT
SCHEMBL25716455	0.87	EGFR (0.39)	LCKFYNCSF1RLYNKIT
SCHEMBL25715151	0.86	BTK (0.40)	LCKFYNCSF1RLYNKIT
SCHEMBL25716378	0.84	BTK (0.40)	LCKFYNCSF1RLYNKIT
SCHEMBL25718320	0.82	GCK (0.37)	BTKEGFRKCNH2ABL1GCK
SCHEMBL25716405	0.79	CYP3A4 (0.45)	LCKFYNCSF1RLYNKIT
SCHEMBL25715301	0.78	KDR (0.38)	LCKFYNCSF1RLYNKIT
SCHEMBL25716316	0.77	EPHB4 (0.40)	LCKFYNCSF1RLYNKIT
SCHEMBL25714979	0.73	BTK (0.46)	LCKFYNCSF1RLYNKIT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2023104035-A1	SUBSTITUTED MONOCYCLIC OR BICYCLIC HETEROCYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF	英矽智能科技(上海)有限公司	2023-06-15	—	—	WO	disclosed