Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 10/20 | 0.40 |
| ▸ | EGFR | P00533 | 4/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | FGFR4 | P22455 | 4/20 | 0.38 |
| ▸ | LCK | P06239 | 2/20 | 0.37 |
| ▸ | FYN | P06241 | 2/20 | 0.37 |
| ▸ | CSF1R | P07333 | 2/20 | 0.37 |
| ▸ | LYN | P07948 | 2/20 | 0.37 |
| ▸ | KIT | P10721 | 2/20 | 0.37 |
| ▸ | SRC | P12931 | 2/20 | 0.37 |
| ▸ | FLT1 | P17948 | 2/20 | 0.37 |
| ▸ | FLT4 | P35916 | 2/20 | 0.37 |
| ▸ | KDR | P35968 | 2/20 | 0.37 |
| ▸ | FLT3 | P36888 | 2/20 | 0.37 |
| ▸ | BLK | P51451 | 2/20 | 0.37 |
| ▸ | GCK | P35557 | 1/20 | 0.37 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.35 |
| ▸ | DHODH | Q02127 | 1/20 | 0.35 |
| ▸ | DRD1 | P21728 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25715151 | 0.90 | BTK (0.40) | BTKEGFRKCNH2LCKFYN | |
| SCHEMBL25716441 | 0.87 | LCK (0.36) | BTKEGFRKCNH2FGFR4LCK | |
| SCHEMBL25716455 | 0.87 | EGFR (0.39) | BTKEGFRKCNH2FGFR4LCK | |
| SCHEMBL25715211 | 0.84 | LCK (0.36) | BTKEGFRKCNH2LCKFYN | |
| SCHEMBL25716316 | 0.81 | EPHB4 (0.40) | BTKEGFRKCNH2FGFR4LCK | |
| SCHEMBL25715238 | 0.80 | LCK (0.34) | BTKEGFRKCNH2FGFR4LCK | |
| SCHEMBL25715301 | 0.80 | KDR (0.38) | BTKEGFRFGFR4LCKFYN | |
| SCHEMBL25716405 | 0.78 | CYP3A4 (0.45) | BTKEGFRFGFR4LCKFYN | |
| SCHEMBL25715149 | 0.78 | MAPK1 (0.36) | BTKEGFRKCNH2FGFR4SRC | |
| SCHEMBL25715071 | 0.75 | BTK (0.49) | BTKEGFRKCNH2FGFR4LCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023104035-A1 | SUBSTITUTED MONOCYCLIC OR BICYCLIC HETEROCYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF | 英矽智能科技(上海)有限公司 | 2023-06-15 | — | — | WO | disclosed |